LAMP2 Proteins, Antibodies, cDNA Clones Research Reagents

All LAMP2 reagents are produced in house and quality controlled, including 14 LAMP2 Antibody, 53 LAMP2 Gene, 1 LAMP2 IP Kit, 3 LAMP2 Lysate, 3 LAMP2 Protein, 3 LAMP2 qPCR. All LAMP2 reagents are ready to use.

LAMP2 Protein (3)

    LAMP2 Antibody (14)

      LAMP2 cDNA Clone (53)


      In expression vector


      LAMP2 Lysate (3)

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        LAMP2 Background

        LAMP2 (Lysosomal-associated membrane protein 2), also known as CD17b (Cluster of Differentiation 17b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.

        LAMP2 References

        • Maron BJ, et al. (2010) Profound left ventricular remodeling associated with LAMP2 cardiomyopathy. Am J Cardiol. 106(8): 1194-6.
        • Di Blasi C, et al. (2008) Danon disease: a novel LAMP2 mutation affecting the pre-mRNA splicing and causing aberrant transcripts and partial protein expression. Neuromuscul Disord. 18(12): 962-6.
        • Echaniz-Laguna A, et al. (2006) Novel Lamp-2 gene mutation and successful treatment with heart transplantation in a large family with Danon disease. Muscle Nerve. 33(3): 393-7.

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