NRAS Proteins, Antibodies, cDNA Clones Research Reagents

All NRAS reagents are produced in house and quality controlled, including 2 NRAS Antibody, 26 NRAS Gene, 1 NRAS Protein, 2 NRAS qPCR. All NRAS reagents are ready to use.

NRAS Protein (1)

    NRAS Antibody (2)

      NRAS cDNA Clone (26)

      NM_002524
      NM_080766.2

      NRAS qPCR Primer (2)

      NRAS Background

      NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the harvey and kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1) and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids. These ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. The NRAS gene specifies two main transcripts of 2Kb and 4.3Kb. The difference between the two transcripts is a simple extension through the termination site of the 2Kb transcript. The NRAS gene consists of seven exons (-I, I, II, III, IV, V, VI).

      NRAS References

      • Marshall CJ. et al., 1982, Nature. 299 (5879): 171-3.
      • Hall Alan. et al., 1983, Nature. 303 (5916): 396-400.
      • McCormick F. 1996, Mol Reprod Dev. 42 (4): 500-6.

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