RKIP/PEBP1 Proteins, Antibodies, cDNA Clones Research Reagents

PEBP1 (Phosphatidylethanolamine Binding Protein 1) is a protein coding gene located on human chromosome 12q24.23. PEBP1 is also known as PBP, HCNP, PEBP, RKIP, HCNPpp, PEBP-1, HEL-210, HEL-S-34 and HEL-S-96. The human PEBP1 gene encodes a 21057 Da protein containing 187 amino acids. The PEBP1 protein is broadly expressed in adrenal, liver and other tissues. Among its related pathways are RET signaling and Paradoxical activation of RAF signaling by kinase inactive BRAF. PEBP1 is related to enzyme binding. MRPL38 is an important paralog of PEBP1 gene. PEBP1 is associated with some diseases, including Myeloid Sarcoma and Lung Cancer.

RKIP/PEBP1 Protein (1)

    RKIP/PEBP1 Antibody (3)

      RKIP/PEBP1 cDNA Clone (32)

      NM_017236.1

      In cloning vector

      NM_001048092.1

      In cloning vector

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      RKIP/PEBP1 Background

      Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons where it is predominantly involved in production of choline acetyltransferase. Deregulated PEBP1 is known to cause cancer, diabetic nephropathy and neurodegenerative diseases like Alzheimer's and dementia.

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