SLITRK6 Proteins, Antibodies, cDNA Clones Research Reagents

SLITRK6 (SLIT And NTRK Like Family Member 6) is a protein coding gene located on human chromosome 13q31.1. SLITRK6 is also known as DFNMYP. The human SLITRK6 gene encodes a 95110 Da protein containing 841 amino acids. The SLITRK6 protein is biasedly expressed in urinary bladder, salivary gland other tissues. SLITRK5 is an important paralog of SLITRK6 gene. SLITRK6 is associated with some diseases, including Deafness And Myopia and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.

SLITRK6 Protein (1)

    SLITRK6 Antibody (1)

      SLITRK6 cDNA Clone (13)

      BC101070

      SLITRK6 qPCR Primer (1)

      SLITRK6 Lysate (1)

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        SLITRK6 Background

        SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can suppress neurite outgrowth. In adult brain, SLITRK6 has a critical role in the development of the inner ear neural circuit.

        SLITRK6 References

        • Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
        • Wiemann S, et al. (2001) Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs. Genome Res. 11(3):422-35.
        • Hartley JL, et al. (2001) DNA Cloning Using In Vitro Site-Specific Recombination. Genome Res. 10 (11):1788-95.

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