CD antigens related to Death Receptor Signaling

CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.

Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.

CD antigens chart related to Death Receptor Signaling

Name Name in pathway Alias Function
CD95 Fas Apo-1, FASLG, APTL, TNFRSF6 Induces apoptosis
CD120a TNFR1 TNFR-I, TNFRSF1A, TNFR1 Receptor for TNF
CD178 FASL FasL, CD95L, FASLG, Fas Ligand T-cell mediated cytotoxicity
CD253 TRAIL TRAIL, Apo-2L, TL2, TNFSF10 Induces cell death by apoptosis
CD261 DR4 TRAIL-R1, DR4, TNFRSF10A Induces apoptosis, promotes activation of NFkB
CD262 DR5 TRAIL-R2, DR5, TNFRSF10B Activated by TNFSF10 / TRAIL and transduces apoptosis signal
CD264 DcR2 DCR2, TRAIL-R4, TNFRSF10D Receptor for TRAIL, inhibits apoptosis
CD271 P75 NGFR, p75 (NTR) Regulates neuronal growth, migration, differentiation and cell death during stem cells.
CD358 DR6 TNFRSF21 May activate NFkB and promote apoptosis. May activate JNK and be lymphocytes. involved in T-cell differentiation. Required for both normal cell body death and axonal pruning