CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
|Name||Name in pathway||Alias||Function|
|CD11a||Integrins||LFA-1, LFA1A, ITGAL||Intracellular adhesion and costimulation.|
|CD11c||Integrins||p150, 95, CR4, integrin αX, LFA-1A, ITGAX||Cell adhesion|
|CD18||Integrins||Integrin β2, ITGB2, MFI7||Adhesion, cell signaling|
|CD29||Integrins||Integrin β1, ITGB1, FNRB||Lymphocyte and endothelial adhesion, lymphocyte trafficking and transvascular migration|
|CD41||Integrins||ITGA2B||Platelet activation and aggregation.|
|CD49b||Integrins||VLA-2, ITGA2||Adhesion and platelet aggregation.|
|CD49c||Integrins||VLA-3, ITGA3||Adhesion and signal transduction|
|CD49e||Integrins||VLA-5, ITGA5||Adhesion, regulation of cell survival and apoptosis|
|CD49f||Integrins||VLA-6, ITGA6||Embryogenesis, adhesion and cell migration|
|CD51||Integrins||Vitronectin receptor, ITGAV, MSK8||Adhesion and signal transduction|
|CD61||Integrins||GPIIIa, ITGB3, GP3A||Cell adhesion|
|CD103||Integrins||HUMINAE, ITGA1||Lymphocyte retention. Receptor for E-cadherin.|