CD11b antigens

CD11b antigens general information

CD11b Gene ID 3684
CD11b Official Full Name integrin subunit alpha M
CD11b Alias ITGAM, CR3A, MO1A, MAC-1, MAC1A, SLEB6
CD11b Cellular Expression T; B; NK; Dendritic; Macrophage; monocytes
CD11b Ligand/Receptor/Association CD54, iC3b and ECM , CD242
CD11b Function cell adhesion, and immune response
CD11b Summary This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.