CD249 antigens

CD249 antigens general information

CD249 Gene ID 2028
CD249 Official Full Name glutamyl aminopeptidase
CD249 Alias Aminopeptidase AM, EAP, ENPEP
CD249 Cellular Expression Endothelial; Epithelial
CD249 Ligand/Receptor/Association  
CD249 Function Converts angiotensin II to angiotensin III.
CD249 Summary Glutamyl aminopeptidase (EC 3.4.11.7, aminopeptidase A, aspartate aminopeptidase, angiotensinase A, glutamyl peptidase, Ca2+-activated glutamate aminopeptidase, membrane aminopeptidase II, antigen BP-1/6C3 of mouse B lymphocytes, L-aspartate aminopeptidase, angiotensinase A2) is an enzyme encoded by the ENPEP gene. Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.[1]

Information from NCBI or Wiki

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