CD257 antigens

CD257 antigens general information

CD257 Gene ID 10673
CD257 Official Full Name tumor necrosis factor superfamily member 13b
CD257 Alias BLyS, BAFF, TALL-1, TNFSF13B
CD257 Cellular Expression T; B; NK; Dendritic; Granulocyte; Macrophage; monocytes
CD257 Ligand/Receptor/Association TACI, BCMA, BAFF-R
CD257 Function Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity
CD257 Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

Information from NCBI or Wiki

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