CD326 antigens

CD326 antigens general information

CD326 Gene ID 4072
CD326 Official Full Name epithelial cell adhesion molecule
CD326 Alias Ep-CAM, Ly74,, EGP314, TROP-1, TACSTD1
CD326 Cellular Expression Epithelial
CD326 Ligand/Receptor/Association LAIR-1, LAIR-2, Ep-CAM
CD326 Function A homotypic calcium-independent T-cell adhesion molecule
CD326 Summary The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Information from NCBI or Wiki

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