CD354 antigens

CD354 antigens general information

CD354 Gene ID 54210
CD354 Official Full Name triggering receptor expressed on myeloid cells 1
CD354 Alias TREM-1
CD354 Cellular Expression T; B; NK; Dendritic; Granulocyte; Macrophage; monocytes
CD354 Ligand/Receptor/Association  
CD354 Function Stimulates neutrophil and monocyte-mediated inflammatory responses.Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers
CD354 Summary This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

Information from NCBI or Wiki

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