CD36 antigens

CD36 antigens general information

CD36 Gene ID 948
CD36 Official Full Name CD36 molecule
CD36 Alias GPIV, GP3B, GP4, SCARB3
CD36 Cellular Expression Dendritic; Endothelial; Erythrocyte; Macrophage; monocytes; Platelet; Stem cell
CD36 Ligand/Receptor/Association oxidized LDL, thrombospondin, collagen
CD36 Function Cell adhesion, cholesterol transport, scavenger receptor
CD36 Summary The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

Information from NCBI or Wiki

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