CD366 antigens

CD366 antigens general information

CD366 Gene ID 84868
CD366 Official Full Name hepatitis A virus cellular receptor 2
CD366 Alias HAVCR2, TIM-3, TIMD3
CD366 Cellular Expression T; Dendritic; monocytes
CD366 Ligand/Receptor/Association Galectin-9
CD366 Function T-cell exhaustion, immune checkpoint
CD366 Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.