CD4 antigens

CD4 antigens general information

CD4 Gene ID 920
CD4 Official Full Name CD4 molecule
CD4 Alias T4
CD4 Cellular Expression T; Granulocyte; Macrophage; monocytes
CD4 Ligand/Receptor/Association MHC class II, HIV gp120, IL-16
CD4 Function T-cell activation, thymic differentiation and receptor for HIV
CD4 Summary This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.