CD66b antigens

CD66b antigens general information

CD66b Gene ID 1088
CD66b Official Full Name carcinoembryonic antigen related cell adhesion molecule 8
CD66b Alias CD67, CGM6, CEACAM8
CD66b Cellular Expression Granulocyte
CD66b Ligand/Receptor/Association CD66c
CD66b Function Cell adhesion and neutrophil activation
CD66b Summary The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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