CD66c antigens

CD66c antigens general information

CD66c Gene ID 4680
CD66c Official Full Name carcinoembryonic antigen related cell adhesion molecule 6
CD66c Alias NCA, CEACAM6
CD66c Cellular Expression Epithelial; Granulocyte
CD66c Ligand/Receptor/Association CD66a, b, c, e
CD66c Function Cell adhesion and neutrophil activation
CD66c Summary This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]

Information from NCBI or Wiki

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