CD68 antigens

CD68 antigens general information

CD68 Gene ID 968
CD68 Official Full Name CD68 molecule
CD68 Alias Macrosialin, gp110, KP1
CD68 Cellular Expression Dendritic; Epithelial; monocytes
CD68 Ligand/Receptor/Association oxidized LDL
CD68 Function Macrophage homing
CD68 Summary This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.