Anti-Clusterin Antibody

1/3
Price:
Size:
Number:

Anti-Clusterin Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-Clusterin Antibody
Validated applications
IHC-P
Species reactivity
Reacts with: Human
Specificity
Human Clusterin
Has cross-reactivity in ELISA with
Mouse CLU
Immunogen
Recombinant Human Clusterin / Apolipoprotein J / Apo-J / CLU protein (Catalog#11297-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human Clusterin / Apolipoprotein J / Apo-J / CLU (rh Clusterin / Apolipoprotein J / Apo-J / CLU; Catalog#11297-H08H; NP_001822.2; Met1-Glu501).
Source
Monoclonal Rabbit IgG Clone #210
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Clusterin Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Clusterin Antibody (Rabbit Monoclonal antibody) Images

Immunochemical staining of human CLU in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human CLU in human ovarian cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human CLU in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Anti-Clusterin Antibody: Alternative Names

Anti-AAG4 Antibody; Anti-APO-J Antibody; Anti-APOJ Antibody; Anti-CLI Antibody; Anti-CLU1 Antibody; Anti-CLU2 Antibody; Anti-KUB1 Antibody; Anti-NA1/NA2 Antibody; Anti-SGP-2 Antibody; Anti-SGP2 Antibody; Anti-SP-40 Antibody; Anti-TRPM-2 Antibody; Anti-TRPM2 Antibody

Clusterin Background Information

Clusterin, also known as complement-associated protein SP-4, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Full Name
clusterin
References
  • Silkensen JR, et al. (1994) The role of clusterin in tissue injury. Biochem Cell Biol. 72(11-12): 483-8.
  • Naik RR, et al. (2002) Biomimetic synthesis and patterning of silver nanoparticles. Nat Mater. 1(3): 169-72.
  • Djeu JY, et al. (2009) Clusterin and chemoresistance. Adv Cancer Res. 105: 77-92.
Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait