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쥐 RPRD1B Gene ORF cDNA clone expression plasmid, N-OFPSpark 태그

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
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14027-H07H-20
14027-H07H-100
20 µg 
100 µg 
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반응성: Human  
신청: WB  
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14027-MM01-50
14027-MM01-200
14027-MM01-100
50 µg 
200 µg 
100 µg 
Add to Cart
반응성: Human  
신청: WB  IHC-P  IP  
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  • Slide 1
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14027-T44-50
14027-T44-200
14027-T44-100
50 µg 
200 µg 
100 µg 
Add to Cart

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RPRD1B cdna-clone 연구배경

RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. RNA polymerase II C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. RPRD1B is a transcriptional regulator which enhances expression of CCND1. It also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A.

 RPRD1B cdna-clone 참고자료
  • Ni Z. et al., 2011, Transcription. 2 (5): 237-42.
  • Kristensen AR. et al., 2012, Nat Methods. 9 (9): 907-9.
  • Woods NT. et al., 2012, Sci Signal.5 (242): rs6.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".