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휴먼 CD62L/L-Selectin Gene ORF cDNA clone expression plasmid

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
11838-H08H-200
11838-H08H-100
200 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50045-M03H-200
50045-M03H-100
200 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
50045-M08H-200
50045-M08H-100
200 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90168-C08H-200
90168-C08H-100
200 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90168-C02H-200
90168-C02H-100
200 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
90169-C08H-200
90169-C08H-100
200 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  FCM  
  • Slide 1
11838-MM01-50
11838-MM01-200
11838-MM01-100
50 µg 
200 µg 
100 µg 
Add to Cart
반응성: Human  
신청: FCM  
  • Slide 1
  • Slide 1
11838-MM01-P-25
11838-MM01-P-100
25 Test 
100 Tests 
Add to Cart
반응성: Human  
신청: FCM  
  • Slide 1
11838-MM01-A-25
11838-MM01-A-100
25 Test 
100 Tests 
Add to Cart
반응성: Human  
신청: ELISA  
    11838-RP02-50
    11838-RP02-200
    11838-RP02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: 
      11838-R037-50
      11838-R037-100
      11838-R037-1
      50 µg 
      100 µg 
      1 mg 
      Add to Cart
      반응성: Human  
      신청: ELISA  
        11838-RP01-400
        11838-RP01-200
        11838-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        반응성: Human  
        신청: ELISA  
          11838-R018-50
          11838-R018-100
          11838-R018-1
          50 µg 
          100 µg 
          1 mg 
          Add to Cart
          반응성: Human  
          신청: 
          • Slide 1
          11838-MM01-C-25
          11838-MM01-C-100
          25 Test 
          100 Tests 
          Add to Cart
          반응성: Mouse  
          신청: FCM  
          • Slide 1
          • Slide 1
          50045-R414-F-25
          50045-R414-F-100
          25 Test 
          100 Tests 
          Add to Cart
          반응성: Mouse  
          신청: ELISA  
            50045-RP01-400
            50045-RP01-200
            50045-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            반응성: Mouse  
            신청: ELISA  
              50045-R023-50
              50045-R023-100
              50045-R023-1
              50 µg 
              100 µg 
              1 mg 
              Add to Cart
              반응성: Mouse  
              신청: IHC-P  
              • Slide 1
              50045-R122-50
              50045-R122-100
              50 µg 
              100 µg 
              Add to Cart
              반응성: Mouse  
              신청: ELISA  
                50045-RP02-50
                50045-RP02-200
                50045-RP02-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                반응성: Mouse  
                신청: FCM  
                • Slide 1
                • Slide 1
                50045-R414-A-25
                50045-R414-A-100
                25 Test 
                100 Tests 
                Add to Cart
                반응성: Mouse  
                신청: FCM  
                • Slide 1
                • Slide 1
                50045-R414-P-25
                50045-R414-P-100
                25 Test 
                100 Tests 
                Add to Cart
                반응성: Mouse  
                신청: 
                • Slide 1
                50045-R414-50
                50045-R414-100
                50 µg 
                100 µg 
                Add to Cart
                반응성: Mouse  
                신청: FCM  
                • Slide 1
                50045-R414-C-25
                50045-R414-C-100
                25 Test 
                100 Tests 
                Add to Cart
                반응성: RAT  
                신청: WB  IHC-P  
                • Slide 1
                • Slide 1
                102346-T40-50
                102346-T40-200
                102346-T40-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart

                CD62L/L-Selectin ELISA Pair Set

                검출 한계:
                SEK11838-5
                SEK11838-15
                5 Plates 
                15 Plates 
                Add to Cart
                검출 한계: 12.5 pg/ml
                SEK50045-5
                SEK50045-15
                5 Plates 
                15 Plates 
                Add to Cart

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                CD62L/L-Selectin cdna-clone 연구배경

                L-selectin (SELL), also known as CD62L, is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues. It belongs to the selectin family of proteins, and consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. L-selectin is the only selectin expressed on leukocytes and mediates a number of leukocyte-endothelial interactions. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point. L-selectin-mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. In addition, L-selectin-mediated entry into peripheral lymph nodes is required for optimal induction of lymphocyte homeostatic proliferation during lymphopenia. Importantly, L-selectin has been shown to have both adhesive and signaling functions during leukocyte migration. L-selectin has also been shown to mediate leukocyte recruitment during chronic inflammatory and autoimmune diseases and thus is a potential therapeutic target for drug development.

                 CD62L/L-Selectin cdna-clone 참고자료
              • Smalley DM, et al. (2005) L-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med. 9(2): 255-66.
              • Grailer JJ, et al. (2009) L-selectin: role in regulating homeostasis and cutaneous inflammation. J Dermatol Sci. 56(3): 141-7.
              • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".