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휴먼 Leukemia Inhibitory Factor/LIF Gene ORF cDNA clone expression plasmid, C-OFPSpark 태그

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
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14890-H08H-5
14890-H08H-20
14890-H08H-100
5 µg 
20 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
14890-H02H-5
14890-H02H-20
14890-H02H-100
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20 µg 
100 µg 
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발현 숙주: Human Cells  
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14890-HNAH-50
14890-HNAH-20
50 µg 
20 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
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50755-M08H-5
50755-M08H-20
50755-M08H-100
5 µg 
20 µg 
100 µg 
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제품 설명:   
발현 숙주: Human Cells  
  • Slide 1
50756-MNAH-5
50756-MNAH-20
50756-MNAH-100
5 µg 
20 µg 
100 µg 
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반응성: Mouse  
신청: ELISA  
    50755-RP01-400
    50755-RP01-200
    50755-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Mouse  
    신청: ELISA  WB  IP  
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    • Slide 1
    50755-T52-50
    50755-T52-200
    50755-T52-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Mouse  
    신청: ELISA  
      50756-RP01-400
      50756-RP01-200
      50756-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Mouse  
      신청: ELISA  
        50756-T16-50
        50756-T16-200
        50756-T16-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart

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        Leukemia Inhibitory Factor/LIF cdna-clone 연구배경

        Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It’s involved in growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. LIF has potent proinflammatory property, being the inducer of the acute phase protein synthesis and affecting the cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic and neuronal cells. LIF binds to the specific LIF receptor (LIFR-α) which forms a heterodimer with a specific subunit common to all members of that family of receptors, the GP130 signal transducing subunit. This leads to activation of the JAK/STAT and MAPK cascades. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origin.

         Leukemia Inhibitory Factor/LIF cdna-clone 참고자료
      • Salas EM, et al. (2011) LIF, a Novel STAT5-Regulated Gene, Is Aberrantly Expressed in Myeloproliferative Neoplasms. Genes Cancer. 2 (5): 593-6.
      • Chodorowska G, et al. (2004) Leukemia inhibitory factor (LIF) and its biological activity. Ann Univ Mariae Curie Sklodowska Med. 59 (2): 189-93.
      • Garcia-Campana AM, et al. (2007) LIF detection of peptides and proteins in CE. Electrophoresis. 28 (1-2): 208-32.
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