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휴먼 CD276 / B7-H3, Biotinylated HEK293 Cell Lysate (WB 양성대조군)

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
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11188-H08H-50
11188-H08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
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11188-H02H-50
11188-H02H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
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11188-H08H-B-50
11188-H08H-B-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
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50973-M08H-50
50973-M08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
50973-M08H-B-50
50973-M08H-B-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
80380-R08H-50
80380-R08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
80380-R02H-50
80380-R02H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
90806-C08H-20
90806-C08H-100
20 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
90806-C02H-50
90806-C02H-200
50 µg 
200 µg 
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반응성: Human  
신청: FCM  
  • Slide 1
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11188-MM06-P-25
11188-MM06-P-100
25 Test 
100 Tests 
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반응성: Human  
신청: FCM  
  • Slide 1
  • Slide 1
11188-MM06-F-25
11188-MM06-F-100
25 Test 
100 Tests 
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반응성: Human  
신청: 
    11188-MM01-50
    11188-MM01-200
    11188-MM01-100
    11188-MM01-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
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    반응성: Human  
    신청: ELISA  FCM  IF  ICC/IF  
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    11188-MM06-50
    11188-MM06-200
    11188-MM06-100
    11188-MM06-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
    Add to Cart
    반응성: Human  
    신청: FCM  
    • Slide 1
    11188-MM06-A-25
    11188-MM06-A-100
    25 Test 
    100 Tests 
    Add to Cart
    반응성: Human  
    신청: ELISA  IP  
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    • Slide 1
    11188-RP02-50
    11188-RP02-200
    11188-RP02-100
    50 µg 
    200 µg 
    100 µg 
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    반응성: Mouse  
    신청: ELISA  
      50973-RP01-400
      50973-RP01-200
      50973-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      반응성: Mouse  
      신청: ELISA  WB  IP  
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      50973-T52-50
      50973-T52-200
      50973-T52-100
      50 µg 
      200 µg 
      100 µg 
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      반응성: Rat  
      신청: ELISA  
        80380-RP01-400
        80380-RP01-200
        80380-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        반응성: Rat  
        신청: ELISA  WB  IP  
        • Slide 1
        • Slide 1
        80380-T52-50
        80380-T52-200
        80380-T52-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart

        B7-H3/CD276 ELISA Pair Set

        검출 한계:
        SEK11188-5
        SEK11188-15
        5 Plates 
        15 Plates 
        Add to Cart

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        B7-H3/CD276 lysate_category 연구배경

        B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.

        Immune Checkpoint
        Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
        Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

        Immunotherapy   Cancer Immunotherapy   Targeted Therapy

         B7-H3/CD276 lysate_category 참고자료
      • Suh WK, et al. (2004) The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization. Proc Natl Acad Sci U S A. 101(35): 12969-73.
      • Waschbisch A, et al. (2008) Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions. Arthritis Rheum. 58(11): 3600-8.
      • Loos M, et al. (2010) B7-h3 and its role in antitumor immunity. Clin Dev Immunol. 2010: 683875.
      • Zang X, et al. (2010) Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas. Mod Pathol. 23(8): 1104-12.
      • Sun J, et al. (2010) Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma. Cancer Immunol Immunother. 59(8): 1163-71.
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