Hemagglutinin / HA Protein

Hemagglutinin / HA Protein Overview

Hemagglutinin / HA reagents

Takahashi et al. (2003) searched for genes expressed specifically in murine embryonic stem (ES) cells by digital differential display analysis and identified the ERas gene. They obtained a full-length cDNA encoding ERas by RACE. The predicted 227-amino acid ERas protein shares 43%, 46%, and 47% identity with HRas (190020), KRas (190070), and NRas (164790), respectively, and 5 domains essential for small G proteins are highly conserved. ERas contains a CAAX motif and is located in a cytoplasmic membrane. Northern blot analysis detected a 1.2-kb ERas transcript in several undifferentiated mouse ES cell lines. By searching human genomic databases, Takahashi et al. (2003) found that the ERas gene is most similar to the HRAS2 gene, which is located on the X chromosome, like mouse ERas. HRAS2, or HRASP, was considered to be a processed pseudogene with several nonsense deletion mutations (Land et al., 1983; Miyoshi et al., 1984). However, Takahashi et al. (2003) resequenced HRAS2 and determined that the reported mutations do not exist. The predicted 227-amino acid HRAS2 protein shares 76% identity with the mouse ERas protein. Because of the sequence similarity and the common chromosomal localization, Takahashi et al. (2003) concluded that HRAS2 is the human homolog of mouse ERas.

Recombinant Hemagglutinin / HA Protein Feature

Influenza B (B/Brisbane/60/2008) Hemagglutinin / HA Protein (His Tag)

High Purity
> 95 % as determined by SDS-PAGE.
Low Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.

Recombinant Hemagglutinin / HA protein citations

Title
Development and characterization of chitosan coated poly-(ɛ-caprolactone) nanoparticulate system for effective immunization against influenza
Year
2011
Author
Gupta, NK;Tomar, P;Sharma, V;Dixit, VK;
Journal
Vaccine
Title
Evolution of H5N1 influenza virus through proteotyping of hemagglutinin with high resolution mass spectrometry
Year
2011
Author
Ha, JW;Downard, KM;
Journal
Analyst
Title
Grafting material for genetic and cell therapy
Year
2011
Author
O Mazda, T Kishida
Journal
US 20130052170 A1
Title
Human monoclonal antibodies derived from human b cells and having neutralizing activity against influenza a viruses
Year
2011
Author
SJ Chang, JM Kim, KS Yi, HJ Lee
Journal
US 20130004505 A1
Title
Intranasal immunization with recombinant HA and mast cell activator C48/80 elicits protective immunity against 2009 pandemic H1N1 influenza in mice
Year
2011
Author
Meng, S;Liu, Z;Xu, L;Li, L;Mei, S;Bao, L;Deng, W;Li, L;Lei, R;Xie, L;Qin, C;Zhang, L;
Journal
PLoS ONE
Title
Means and methods for producing high affinity antibodies
Year
2011
Author
T Beaumont, MJ Kwakkenbos, H Spits…
Journal
US 20130331552 A1
Title
An inhalational antiviral strategy for the potential use of nitric oxide during influenza infection
Year
2012
Author
McMullin, BB;
Journal
Thesis
Title
Binding Molecule Having Influenza A Virus-Neutralizing Activity Produced from Human B Cell
Year
2012
Author
SJ Chang, KS Kwon, KS Yi, HJ Lee…
Journal
US 20140234336 A1
Title
Immobilized sialyloligo-macroligand and its protein binding specificity
Year
2012
Author
Narla, SN;Sun, XL;
Journal
Biomacromolecules
Title
Increased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus
Year
2012
Author
Josset, L;Engelmann, F;Haberthur, K;Kelly, S;Park, B;Kawoaka, Y;García-Sastre, A;Katze, MG;Messaoudi, I;
Journal
J. Virol.
Title
Molecular adjuvant Ag85A enhances protection against influenza A virus in mice following DNA vaccination
Year
2012
Author
Dai, J;Pei, D;Wang, B;Kuang, Y;Ren, L;Cao, K;Wang, H;Zuo, B;Shao, J;Li, S;Li, H;Li, M;
Journal
Viruses
Title
Molecular adjuvant Ag85A enhances protection against influenza A virus in mice following DNA vaccination
Year
2012
Author
Dai, J;Pei, D;Wang, B;Kuang, Y;Ren, L;Cao, K;Wang, H;Zuo, B;Shao, J;Li, S;Li, H;Li, M;
Journal
Viruses
Title
Seasonal H1N1 influenza virus infection induces cross-protective pandemic H1N1 virus immunity through a CD8-independent, B cell-dependent mechanism
Year
2012
Author
Fang, Y;Banner, D;Kelvin, AA;Huang, SS;Paige, CJ;Corfe, SA;Kane, KP;Bleackley, RC;Rowe, T;Leon, AJ;Kelvin, DJ;
Journal
J. Virol.
Title
Setting up a platform for plant-based influenza virus vaccine production in South Africa
Year
2012
Author
Mortimer, E;Maclean, JM;Mbewana, S;Buys, A;Williamson, AL;Hitzeroth, II;Rybicki, EP;
Journal
BMC Biotechnol.
Title
Thermal-sensitive hydrogel as adjuvant-free vaccine delivery system for H5N1 intranasal immunization
Year
2012
Author
Wu, Y;Wei, W;Zhou, M;Wang, Y;Wu, J;Ma, G;Su, Z;
Journal
Biomaterials
Title
A polyvalent influenza A DNA vaccine induces heterologous immunity and protects pigs against pandemic A(H1N1)pdm09 virus infection
Year
2013
Author
Bragstad, K;Vinner, L;Hansen, MS;Nielsen, J;Fomsgaard, A;
Journal
Vaccine
Title
Aptamers that bind to the hemagglutinin of the recent pandemic influenza virus H1N1 and efficiently inhibit agglutination
Year
2013
Author
Gopinath, SC;Kumar, PK;
Journal
Acta Biomater
Title
Broad-spectrum detection of h5 subtype influenza a viruses with a new fluorescent immunochromatography system
Year
2013
Author
Sakurai, A;Takayama, K;Nomura, N;Munakata, T;Yamamoto, N;Tamura, T;Yamada, J;Hashimoto, M;Kuwahara, K;Sakoda, Y;Suda, Y;Kobayashi, Y;Sakaguchi, N;Kida, H;Kohara, M;Shibasaki, F;
Journal
PLoS ONE
Title
Comparative glycomics analysis of influenza Hemagglutinin (H5N1) produced in vaccine relevant cell platforms
Year
2013
Author
An, Y;Rininger, JA;Jarvis, DL;Jing, X;Ye, Z;Aumiller, JJ;Eichelberger, M;Cipollo, JF;
Journal
J. Proteome Res.
Title
Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies
Year
2013
Author
S Jegaskanda, ER Job, M Kramski…
Journal
The Journal of Immunology
Title
Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies
Year
2013
Author
S Jegaskanda, ER Job, M Kramski…
Journal
The Journal of Immunology
Title
DESIGN, SYNTHESIS AND CHARACTERIZATION OF CHAIN-END FUNCTIONALIZED GLYCO-POLYMER FOR EFFICIENT PROTEOMIC ANALYSIS
Year
2013
Author
Satya, NN;
Journal
Thesis
Title
Development of influenza H7N9 virus like particle (VLP) vaccine: Homologous A/Anhui/1/2013 (H7N9) protection and heterologous A/chicken/Jalisco/CPA1/2012 ( …
Year
2013
Author
GE Smith, DC Flyer, R Raghunandan, Y Liu, Z Wei…
Journal
Vaccine
Title
Differential activity of type I interferon subtypes for dendritic cell differentiation
Year
2013
Author
G Garcin, Y Bordat, P Chuchana, D Monneron…
Journal
PloS one
Title
Evaluation of Anti-A/Udorn/307/1972 Antibody Specificity to Influenza A/H3N2 Viruses Using an Evanescent-Field Coupled Waveguide-Mode Sensor
Year
2013
Author
Gopinath, SC;Awazu, K;Fujimaki, M;Shimizu, K;
Journal
PLoS ONE
Title
Generation of anti-influenza aptamers using the systematic evolution of ligands by exponential enrichment for sensing applications
Year
2013
Author
Lakshmipriya, T;Fujimaki, M;Gopinath, SC;Awazu, K;
Journal
Langmuir
Title
Glassy compositions
Year
2013
Author
RA Hyde, LL Wood
Journal
US Patent 8,512,679
Title
Glassy compositions
Year
2013
Author
RA Hyde, LL Wood
Journal
US Patent 8,512,679
Title
Immunogenicity and safety of H1N1 influenza hemagglutinin protein expressed in a baculovirus system
Year
2013
Author
Na, HN;Kim, KH;Song, MK;Park, HL;Lee, EY;Shim, SH;Park, S;Nam, JH;
Journal
Microbiol. Immunol.
Title
Impact of dynamical hydration shell around HA protein on nonlinear concentration dependent T-rays absorption
Year
2013
Author
Sun, Y;Wang, T;Chen, S;Zuo, J;Zhang, Z;
Journal
Journal of Innovative Optical Health Sciences
Title
In vitro and in vivo characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin
Year
2013
Author
Mallajosyula, VV;Citron, M;Lu, X;Meulen, JT;Varadarajan, R;Liang, X;
Journal
Proteins
Title
Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus
Year
2013
Author
Dong, J;Sakurai, A;Nomura, N;Park, EY;Shibasaki, F;Ueda, H;
Journal
PLoS ONE
Title
Mucosal application of gp140 encoding DNA polyplexes to different tissues results in altered immunological outcomes in mice
Year
2013
Author
Mann, JF;McKay, PF;Arokiasamy, S;Patel, RK;Tregoning, JS;Shattock, RJ;
Journal
PLoS ONE
Title
Neu5Acα2,6Gal and Neu5Acα2,3Gal receptor specificities on influenza viruses determined by a waveguide-mode sensor
Year
2013
Author
Gopinath, SC;Awazu, K;Fujimaki, M;Shimizu, K;
Journal
Acta Biomater
Title
Probing label free antibody interactions with HA protein using terahertz pulsed spectroscopy
Year
2013
Author
Sun, Y;Zuo, J;Zhang, Z;Zhang, C;
Journal
Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2013 38th International Conference
Title
Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection
Year
2013
Author
Mann, JF;McKay, PF;Arokiasamy, S;Patel, RK;Klein, K;Shattock, RJ;
Journal
J Control Release
Title
Side chain requirements for affinity and specificity in D5, an HIV-1 antibody derived from the VH1-69 germline segment
Year
2013
Author
Stewart, A;Harrison, JS;Regula, LK;Lai, JR;
Journal
BMC Biochem.
Title
T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study
Year
2013
Author
Duvvuri, VR;Duvvuri, B;Jamnik, V;Gubbay, JB;Wu, J;Wu, GE;
Journal
BMC Infect. Dis.
Title
Toward animal cell culture-based influenza vaccine design: viral hemagglutinin N-glycosylation markedly impacts immunogenicity
Year
2013
Author
Hütter, J;Rödig, JV;Höper, D;Seeberger, PH;Reichl, U;Rapp, E;Lepenies, B;
Journal
J. Immunol.
Title
3-O-galloylated procyanidins from Rumex acetosa L. inhibit the attachment of influenza A virus
Year
2014
Author
A Derksen, A Hensel, W Hafezi, F Herrmann…
Journal
PloS one
Title
A Combination of Serological Assays to Detect Human Antibodies to the Avian Influenza A H7N9 Virus
Year
2014
Author
Dong, L;Bo, H;Bai, T;Gao, R;Dong, J;Zhang, Y;Guo, J;Zou, S;Zhou, J;Zhu, Y;Xin, L;Li, X;Xu, C;Wang, D;Shu, Y;
Journal
PLoS ONE
Title
A fluorescent aptasensor for H5N1 influenza virus detection based-on the CORE-shell nanoparticles metal-enhanced fluorescence (MEF)
Year
2014
Author
Pang, Y;Wang, J;Xiao, R;Wang, S;
Journal
Biosensors and Bioelectronics
Title
A High-Affinity CDR-Grafted Antibody against Influenza A H5N1 Viruses Recognizes a Conserved Epitope of H5 Hemagglutinin
Year
2014
Author
Xiong, F;Xia, L;Wang, J;Wu, B;Wang, D;Yuan, L;Cheng, Y;Zhu, H;Che, X;Zhang, Q;Zhao, G;Wang, Y;
Journal
PLoS ONE
Title
A Novel Benzenediamine Derivate Rescued Mice from Experimental Sepsis by Attenuating Pro-inflammatory Mediators via IRAK4
Year
2014
Author
Dou, H;Song, Y;Liu, X;Yang, L;Jiang, N;Chen, D;Li, E;Tan, R;Hou, Y;
Journal
Am. J. Respir. Cell Mol. Biol.
Title
A novel neutralizing antibody against diverse clades of H5N1 influenza virus and its mutants capable of airborne transmission
Year
2014
Author
Wu, R;Li, X;Leung, HC;Cao, Z;Qiu, Z;Zhou, Y;Zheng, BJ;He, Y;
Journal
Antiviral Res.
Title
A protein chip based inhibitor screening for influenza neuraminidases: the importance of glycan-specific recognition
Year
2014
Author
J Lee, CW Park, HK Kwon, S Jung, HJ Jeong, IC Kang…
Journal
BioChip Journal
Title
An aptamer that binds efficiently to the hemagglutinins of highly pathogenic avian influenza viruses (H5N1 and H7N7) and inhibits hemagglutinin-glycan interactions
Year
2014
Author
Suenaga, E;Kumar, PK;
Journal
Acta Biomater
Title
Antibodies to influenza virus A/H1N1 hemagglutinin in Type 1 diabetes children diagnosed before, during and after the SWEDISH A(H1N1)pdm09 vaccination campaign 2009-2010
Year
2014
Author
Svensson, M;Ramelius, A;Nilsson, AL;Delli, AJ;Elding Larsson, H;Carlsson, A;Forsander, G;Ivarsson, SA;Ludvigsson, J;Kockum, I;Marcus, C;Samuelsson, U;Örtqvist, E;Lernmark, Å;Better Diabetes Diagnosis (BDD) study group;
Journal
Scand. J. Immunol.
Title
Combining magnetic nanoparticle with biotinylated nanobodies for rapid and sensitive detection of influenza H3N2
Year
2014
Author
M Zhu, Y Hu, G Li, W Ou, P Mao, S Xin…
Journal
Nanoscale Research Letters
Title
Dietary wolfberry supplementation enhances the protective effect of flu vaccine against influenza challenge in aged mice
Year
2014
Author
Du, X;Wang, J;Niu, X;Smith, D;Wu, D;Meydani, SN;
Journal
J. Nutr.
Title
Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants
Year
2014
Author
Retamal, M;Abed, Y;Corbeil, J;Boivin, G;
Journal
J. Gen. Virol.
Title
Humanized antibody neutralizing 2009 pandemic H1N1 virus
Year
2014
Author
Shembekar, N;Mallajosyula, VV;Chaudhary, P;Upadhyay, V;Varadarajan, R;Gupta, SK;
Journal
Biotechnol J
Title
Immunodominant CD4+ T-cell Responses to Influenza A Virus in Healthy Individuals Focus on Matrix 1 and Nucleoprotein
Year
2014
Author
Chen, L;Zanker, D;Xiao, K;Wu, C;Zou, Q;Chen, W;
Journal
J. Virol.
Title
Immunoprotection against influenza virus H9N2 by the oral administration of recombinant Lactobacillus plantarumNC8 expressing hemagglutinin in BALB/c mice
Year
2014
Author
Shi, SH;Yang, WT;Yang, GL;Cong, YL;Huang, HB;Wang, Q;Cai, RP;Ye, LP;Hu, JT;Zhou, JY;Wang, CF;Li, Y;
Journal
Virology
Title
Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection
Year
2014
Author
VVA Mallajosyula, M Citron, F Ferrara…
Journal
CrossMark
Title
Intranasal vaccination with a replication-deficient influenza virus induces heterosubtypic neutralising mucosal IgA antibodies in humans
Year
2014
Author
A Morokutti, T Muster, B Ferko
Journal
Vaccine
Title
Metal enhanced fluorescence on nanoporous gold leaf-based assay platform for virus detection
Year
2014
Author
Rahin Ahmed, S;Hossain, MA;Youn Park, J;
Journal
Biosensors and Bioelectronics
Title
Novel Vaccine Delivery System Induces Robust Humoral and Cellular Immune Responses Based on Multiple Mechanisms
Year
2014
Author
YQ Wang, J Wu, QZ Fan, M Zhou…
Journal
Advanced Healthcare Materials
Title
On-chip graphene oxide aptasensor for multiple protein detection
Year
2014
Author
Ueno, Y;Furukawa, K;Matsuo, K;Inoue, S;Hayashi, K;
Journal
Analytica Chimica Acta
Title
Oral immunization of haemaggulutinin H5 expressed in plant endoplasmic reticulum with adjuvant saponin protects mice against highly pathogenic avian influenza A virus infection
Year
2014
Author
Lee, G;Na, YJ;Yang, BG;Choi, JP;Seo, YB;Hong, CP;Yun, CH;Kim, DH;Sohn, EJ;Kim, JH;Sung, YC;Kim, YK;Jang, MH;Hwang, I;
Journal
Plant Biotechnol. J.
Title
Pandemic H1N1 influenza A directly induces a robust and acute inflammatory gene signature in primary human bronchial epithelial cells downstream of membrane fusion
Year
2014
Author
Paquette, SG;Banner, D;Chi, le TB;Leόn, AJ;Xu, L;Ran, L;Huang, SS;Farooqui, A;Kelvin, DJ;Kelvin, AA;
Journal
Virology
Title
PP4 Is Essential for Germinal Center Formation and Class Switch Recombination in Mice
Year
2014
Author
MY Chen, YP Chen, MS Wu, GY Yu, WJ Lin, TH Tan…
Journal
PloS one
Title
Selection of DNA aptamers that bind to influenza A viruses with high affinity and broad subtype specificity
Year
2014
Author
Shiratori, I;Akitomi, J;Boltz, DA;Horii, K;Furuichi, M;Waga, I;
Journal
Biochem. Biophys. Res. Commun.
Title
The Mechanism of Poly-Galloyl-Glucoses Preventing Influenza A Virus Entry into Host Cells
Year
2014
Author
Hu Ge1., Ge Liu2., Yang-Fei Xiang3,4., Yu Wang1, Chao-Wan Guo2, Nan-Hao Chen1, Ying-Jun Zhang5, Yi-Fei Wang3*, Kaio Kitazato2*, Jun Xu1*
Journal
PLoS ONE
Title
The Split Virus Influenza Vaccine rapidly activates immune cells through Fcγ receptors
Year
2014
Author
WE O'Gorman, H Huang, YL Wei, KL Davis…
Journal
Vaccine
Title
Virus-Specific Antibody Secreting Cell, Memory B-cell, and Sero-Antibody Responses in the Human Influenza Challenge Model
Year
2014
Author
Huang, KY;Li, CK;Clutterbuck, E;Chui, C;Wilkinson, T;Gilbert, A;Oxford, J;Lambkin-Williams, R;Lin, TY;McMichael, AJ;Xu, XN;
Journal
J. Infect. Dis.
Title
Antibodies to Antigenic Site A of Influenza H7 Hemagglutinin Provide Protection against H7N9 Challenge
Year
2015
Author
Schmeisser, F;Vasudevan, A;Verma, S;Wang, W;Alvarado, E;Weiss, C;Atukorale, V;Meseda, C;Weir, JP;
Journal
PLoS ONE
Title
Cross-reactivity of immunoglobulin A secreted on the nasal mucosa in mice nasally inoculated with inactivated H1N1 influenza A viruses in the presence of d-octaarginine-linked polymers
Year
2015
Author
Sakuma, S;Morimoto, N;Nishida, K;Murakami, T;Egawa, T;Endo, R;Kataoka, M;Yamashita, S;Miyata, K;Mohri, K;Ochiai, K;Hiwatari, KI;Koike, S;Tobita, E;Uto, T;Baba, M;
Journal
Eur J Pharm Biopharm
Title
Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding
Year
2015
Author
Nita-Lazar, M;Banerjee, A;Feng, C;Amin, MN;Frieman, MB;Chen, WH;Cross, AS;Wang, LX;Vasta, GR;
Journal
Mol. Immunol.
Title
Immunogenicity and protective efficacy of a Vero cell culture-derived whole-virus H7N9 vaccine in mice and guinea pigs
Year
2015
Author
Wodal, W;Schwendinger, MG;Savidis-Dacho, H;Crowe, BA;Hohenadl, C;Fritz, R;Brühl, P;Portsmouth, D;Karner-Pichl, A;Balta, D;Grillberger, L;Kistner, O;Barrett, PN;Howard, MK;
Journal
PLoS ONE
Title
Immunological characterization of monoclonal antibodies used in rapid influenza diagnostic test for detection of the 2009 pandemic influenza A(H1N1)pdm09 infection
Year
2015
Author
Yi, H;Lee, MS;Lee, JY;Lee, HK;Kang, C;
Journal
J. Microbiol.
Title
Label-free detection and characterization of the binding of hemagglutinin protein and broadly neutralizing monoclonal antibodies using terahertz spectroscopy
Year
2015
Author
Sun, Y;Zhong, J;Zhang, C;Zuo, J;Pickwell-MacPherson, E;
Journal
J Biomed Opt
Title
Neoechinulin B and its analogues as potential entry inhibitors of influenza viruses, targeting viral hemagglutinin
Year
2015
Author
Chen, X;Si, L;Liu, D;Proksch, P;Zhang, L;Zhou, D;Lin, W;
Journal
Eur J Med Chem
Title
Preparation of monoPEGylated Cyanovirin-N's derivative and its anti-influenza A virus bioactivity in vitro and in vivo
Year
2015
Author
Wu, C;Chen, W;Chen, J;Han, B;Peng, Z;Ge, F;Wei, B;Liu, M;Zhang, M;Qian, C;Hou, Z;Liu, G;Guo, C;Wang, Y;Kitazato, K;Yu, G;Zou, C;Xiong, S;
Journal
J. Biochem.
Title
A single dose TMV-HA vaccine protects mice from H5N1 Influenza challenge
Year
2016
Author
Mallajosyula, JK;Jeevan, T;Chikwamba, R;Webby, RJ;McCormick, AA;
Journal
International Journal of Vaccine Research
Title
Anti-Hemagglutinin Antibody Derived Lead Peptides for Inhibitors of Influenza Virus Binding
Year
2016
Author
Memczak, H;Lauster, D;Kar, P;Di Lella, S;Volkmer, R;Knecht, V;Herrmann, A;Ehrentreich-Förster, E;Bier, FF;Stöcklein, WF;
Journal
PLoS ONE
Title
Chimpanzee adenovirus vector-based avian influenza vaccine completely protects mice against lethal challenge of H5N1
Year
2016
Author
Cheng, T;Wang, X;Song, Y;Tang, X;Zhang, C;Zhang, H;Jin, X;Zhou, D;
Journal
Vaccine
Title
Demonstration of d-Octaarginine-Linked Polymers as Promising Adjuvants for Mucosal Vaccination through Influenza Virus Challenge
Year
2016
Author
Miyata, K;Mohri, K;Egawa, T;Endo, R;Morimoto, N;Ochiai, K;Hiwatari, K;Tsubaki, K;Tobita, E;Uto, T;Baba, M;Sakuma, S;
Journal
Bioconjug. Chem.
Title
Demonstration of d-Octaarginine-Linked Polymers as Promising Adjuvants for Mucosal Vaccination through Influenza Virus Challenge
Year
2016
Author
Miyata, K;Mohri, K;Egawa, T;Endo, R;Morimoto, N;Ochiai, K;Hiwatari, K;Tsubaki, K;Tobita, E;Uto, T;Baba, M;Sakuma, S;
Journal
Bioconjug. Chem.
Title
Detection of influenza virus using peroxidase-mimic of gold nanoparticles
Year
2016
Author
Ahmed, SR;Kim, J;Suzuki, T;Lee, J;Park, EY;
Journal
Biotechnol. Bioeng.
Title
Development of an Influenza A Master Virus for Generating High-Growth Reassortants for A/Anhui/1/2013(H7N9) Vaccine Production in Qualified MDCK Cells.
Year
2016
Author
Suzuki, Y;Odagiri, T;Tashiro, M;Nobusawa, E;
Journal
PLoS ONE
Title
Génération d'anticorps monoclonaux neutralisants et dérive antigénique du virus influenza pandémique A (H1N1) 2009
Year
2016
Author
Retamal, M;
Journal
Thesis
Title
Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Year
2016
Author
Wang, W;Sun, X;Li, Y;Su, J;Ling, Z;Zhang, T;Wang, F;Zhang, H;Chen, H;Ding, J;Sun, B;
Journal
Nat Commun
Title
Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients
Year
2016
Author
Hou, D;Ying, T;Wang, L;Chen, C;Lu, S;Wang, Q;Seeley, E;Xu, J;Xi, X;Li, T;Liu, J;Tang, X;Zhang, Z;Zhou, J;Bai, C;Wang, C;Byrne-Steele, M;Qu, J;Han, J;Song, Y;
Journal
Sci Rep
Title
Improving adjuvanticity of quaternized chitosan-based microgels for H5N1 split vaccine by tailoring the particle properties to achieve antigen dose sparing effect
Year
2016
Author
Wang, YQ;Fan, QZ;Liu, Y;Yue, H;Ma, XW;Wu, J;Ma, GH;Su, ZG;
Journal
Int J Pharm
Title
Lipid-induced changes in protein conformation as a means to regulate the immunogenicity of antigens incorporated in tubular immunostimulating complexes
Year
2016
Author
Sanina, NM;Vorobieva, NS;Novikova, OD;Portniagina, OY;Davydova, LA;Shnyrov, VL;Kostetsky, EY;
Journal
Biophysics
Title
Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice
Year
2016
Author
Cho, SY;Kim, J;Lee, JH;Sim, JH;Cho, DH;Bae, IH;Lee, H;Seol, MA;Shin, HM;Kim, TJ;Kim, DY;Lee, SH;Shin, SS;Lm, SH;Kim, HR;
Journal
Sci Rep
Title
Novel magnetic relaxation nanosensors: an unparalleled spin on influenza diagnosis
Year
2016
Author
Shelby, T;Banerjee, T;Kallu, J;Sulthana, S;Zegar, I;Santra, S;
Journal
Nanoscale
Title
Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.
Year
2016
Author
Valkenburg, SA;Zhang, Y;Chan, KY;Leung, K;Wu, JT;Poon, LL;
Journal
J. Infect. Dis.
Title
Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.
Year
2016
Author
Valkenburg, SA;Zhang, Y;Chan, KY;Leung, K;Wu, JT;Poon, LL;
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J. Infect. Dis.
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Protective neutralizing influenza antibody response in the absence of T follicular helper cells
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2016
Author
Miyauchi, K;Sugimoto-Ishige, A;Harada, Y;Adachi, Y;Usami, Y;Kaji, T;Inoue, K;Hasegawa, H;Watanabe, T;Hijikata, A;Fukuyama, S;Maemura, T;Okada-Hatakeyama, M;Ohara, O;Kawaoka, Y;Takahashi, Y;Takemori, T;Kubo, M;
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Nat. Immunol.
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Structure-activity relationships of 3-O-β-chacotriosyl oleanane-type triterpenoids as potential H5N1 entry inhibitors
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2016
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Song, G;Shen, X;Li, S;Li, Y;Si, H;Fan, J;Li, J;Gao, E;Liu, S;
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Eur J Med Chem
Title
Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement
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2016
Author
Dahan, R;Barnhart, BC;Li, F;Yamniuk, AP;Korman, AJ;Ravetch, JV;
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Cancer Cell
Title
Whole-Virus Screening to Develop Synbodies for the Influenza Virus
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2016
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Gupta, N;Lainson, J;Domenyuk, V;Zhao, ZG;Johnston, SA;Diehnelt, CW;
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Bioconjug. Chem.
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1, 8-cineol 作为流感疫苗佐剂提高流感疫苗免疫效果的实验研究
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2017
Author
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Journal
中国免疫学杂志
Title
A Broadly Reactive Human Anti-hemagglutinin Stem Monoclonal Antibody That Inhibits Influenza A Virus Particle Release
Year
2017
Author
Yamayoshi, S;Uraki, R;Ito, M;Kiso, M;Nakatsu, S;Yasuhara, A;Oishi, K;Sasaki, T;Ikuta, K;Kawaoka, Y;
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EBioMedicine
Title
A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin
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2017
Author
Paul, SS;Mok, CK;Mak, TM;Ng, OW;Aboagye, JO;Wohlbold, TJ;Krammer, F;Tan, YJ;
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Antiviral Res.
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A DNA vaccine that targets hemagglutinin to antigen presenting cells protects mice against H7 influenza
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2017
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Andersen, TK;Zhou, F;Cox, R;Bogen, B;Grødeland, G;
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J. Virol.
Title
A DNA vaccine that targets hemagglutinin to antigen presenting cells protects mice against H7 influenza
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2017
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Andersen, TK;Zhou, F;Cox, R;Bogen, B;Grødeland, G;
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J. Virol.
Title
A DNA vaccine that targets hemagglutinin to antigen presenting cells protects mice against H7 influenza
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2017
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Andersen, TK;Zhou, F;Cox, R;Bogen, B;Grødeland, G;
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J. Virol.
Title
A DNA vaccine that targets hemagglutinin to antigen presenting cells protects mice against H7 influenza
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2017
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Andersen, TK;Zhou, F;Cox, R;Bogen, B;Grødeland, G;
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J. Virol.
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Addition of αGal HyperAcute™ technology to recombinant avian influenza vaccines induces strong low-dose antibody responses
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2017
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Chen, WA;Zhang, J;Hall, KM;Martin, CB;Kisselev, S;Dasen, EJ;Vahanian, NN;Link, CJ;Martin, BK;
Journal
PLoS ONE
Title
Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
Year
2017
Author
Ahmed, SR;Neethirajan, S;
Journal
bioRxiv
Title
Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
Year
2017
Author
Ahmed, SR;Neethirajan, S;
Journal
bioRxiv
Title
Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
Year
2017
Author
Ahmed, SR;Neethirajan, S;
Journal
bioRxiv
Title
Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
Year
2017
Author
Ahmed, SR;Neethirajan, S;
Journal
bioRxiv
Title
Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
Year
2017
Author
Ahmed, SR;Neethirajan, S;
Journal
bioRxiv
Title
An α2, 3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
Year
2017
Author
Tanaka, T;Zhou, Y;Tamoto, C;Kurebayashi, Y;Takahashi, T;Suzuki, T;
Journal
Journal of Applied Glycoscience
Title
An α2, 3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
Year
2017
Author
Tanaka, T;Zhou, Y;Tamoto, C;Kurebayashi, Y;Takahashi, T;Suzuki, T;
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Journal of Applied Glycoscience
Title
Androgen supplementation improves some but not all aspects of immune senescence in aged male macaques
Year
2017
Author
Rais, M;Wilson, RM;Urbanski, HF;Messaoudi, I;
Journal
Geroscience
Title
Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls
Year
2017
Author
Lind, A;Freyhult, E;Ramelius, A;Olsson, T;Arnheim-Dahlström, L;Lamb, F;Khademi, M;Ambati, A;Maeurer, M;Lima Bomfim, I;Fink, K;Fex, M;Törn, C;Elding Larsson, H;Lernmark, Å;
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Viral Immunol.
Title
Cell-cultured, live attenuated, X-31ca-based H5N1 pre-pandemic influenza vaccine
Year
2017
Author
Lee, YH;Jang, YH;Seong, BL;
Journal
Virology
Title
Chimeric virus-like particles containing influenza HA antigen and GPI-CCL28 induce long-lasting mucosal immunity against H3N2 viruses
Year
2017
Author
Mohan, T;Berman, Z;Luo, Y;Wang, C;Wang, S;Compans, RW;Wang, BZ;
Journal
Sci Rep
Title
Comparison of a novel microcrystalline tyrosine adjuvant with aluminium hydroxide for enhancing vaccination against seasonal influenza
Year
2017
Author
Heath, MD;Swan, NJ;Marriott, AC;Silman, NJ;Hallis, B;Prevosto, C;Gooch, KE;Skinner, MA;
Journal
BMC Infect. Dis
Title
Comparison of mucosal lining fluid sampling methods and influenza-specific IgA detection assays for use in human studies of influenza immunity
Year
2017
Author
de Silva, TI;Gould, V;Mohammed, NI;Cope, A;Meijer, A;Zutt, I;Reimerink, J;Kampmann, B;Hoschler, K;Zambon, M;Tregoning, JS;
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J. Immunol. Methods
Title
Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors
Year
2017
Author
Horiguchi, Y;Goda, T;Matsumoto, A;Takeuchi, H;Yamaoka, S;Miyahara, Y;
Journal
Biosens Bioelectron
Title
Evaluation of seasonal influenza vaccines for H1N1pdm09 and type B viruses based on a replication-incompetent PB2-KO virus
Year
2017
Author
Ui, H;Yamayoshi, S;Uraki, R;Kiso, M;Oishi, K;Murakami, S;Mimori, S;Kawaoka, Y;
Journal
Vaccine
Title
Exploring novel sero-epidemiological tools—Effect of different storage conditions on longitudinal stability of microarray slides comprising influenza A-, measles- and Streptococcus pneumoniae antigens
Year
2017
Author
Freidl, GS;deBruin, E;Schipper, M;Koopmans, M;
Journal
Journal of Virological Methods
Title
Fibroblast activation protein is dispensable in the anti-influenza immune response in mice
Year
2017
Author
Tan, SY;Chowdhury, S;Polak, N;Gorrell, MD;Weninger, W;
Journal
PLoS ONE
Title
High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals
Year
2017
Author
Ryser, S;Estellés, A;Tenorio, E;Kauvar, LM;Gishizky, ML;
Journal
PLoS ONE
Title
Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles
Year
2017
Author
Yeo, SJ;Bao, DT;Seo, GE;Bui, CT;Kim, DTH;Anh, NTV;Tien, TTT;Linh, NTP;Sohn, HJ;Chong, CK;Shin, HJ;Park, H;
Journal
Sci Rep
Title
Increased humoral immunity by DNA vaccination using an α-tocopherol-based adjuvant
Year
2017
Author
Karlsson, I;Borggren, M;Nielsen, J;Christensen, D;Williams, J;Fomsgaard, A;
Journal
Hum Vaccin Immunother
Title
Investigation of antiviral state mediated by interferon-inducible transmembrane protein 1 induced by H9N2 virus and inactivated viral particle in human endothelial cells
Year
2017
Author
Feng, B;Zhao, L;Wang, W;Wang, J;Wang, H;Duan, H;Zhang, J;Qiao, J;
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Virol. J.
Title
Kallikrein-related peptidase 5 contributes to H3N2 influenza virus infection in human lungs
Year
2017
Author
Magnen, M;Gueugnon, F;Guillon, A;Baranek, T;Thibault, VC;Petit-Courty, A;de Veer, SJ;Harris, J;Humbles, AA;Si-Tahar, M;Courty, Y;
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J. Virol.
Title
Modulation of Immunogenicity and Conformation of HA1 Subunit of Influenza A Virus H1/N1 Hemagglutinin in Tubular Immunostimulating Complexes
Year
2017
Author
Sanina, N;Davydova, L;Chopenko, N;Kostetsky, E;Shnyrov, V;
Journal
Int J Mol Sci
Title
Molecular mechanisms underlying protection against H9N2 influenza virus challenge in mice by recombinant Lactobacillus plantarum with surface displayed HA2-LTB
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2017
Author
Jiang, Y;Yang, G;Wang, Q;Wang, Z;Yang, W;Gu, W;Shi, C;Wang, J;Huang, H;Wang, C;
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J. Biotechnol.
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Molecular mechanisms underlying protection against H9N2 influenza virus challenge in mice by recombinant Lactobacillus plantarum with surface displayed HA2-LTB
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2017
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Jiang, Y;Yang, G;Wang, Q;Wang, Z;Yang, W;Gu, W;Shi, C;Wang, J;Huang, H;Wang, C;
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J. Biotechnol.
Title
Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies
Year
2017
Author
Sanjuan Nandin, I;Fong, C;Deantonio, C;Torreno-Pina, JA;Pecetta, S;Maldonado, P;Gasparrini, F;Ordovas-Montanes, J;Kazer, SW;Kjaer, S;Borley, DW;Nair, U;Coleman, JA;Lingwood, D;Shalek, AK;Meffre, E;Poignard, P;Burton, DR;Batista, FD;
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J. Exp. Med.
Title
Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies
Year
2017
Author
Freedman, JD;Hagel, J;Scott, EM;Psallidas, I;Gupta, A;Spiers, L;Miller, P;Kanellakis, N;Ashfield, R;Fisher, KD;Duffy, MR;Seymour, LW;
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EMBO Mol Med
Title
Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase
Year
2017
Author
Schattauer, SS;Land, BB;Reichard, KL;Abraham, AD;Burgeno, LM;Kuhar, JR;Phillips, PEM;Ong, SE;Chavkin, C;
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Nat Commun
Title
Potent influenza A virus entry inhibitors targeting a conserved region of hemagglutinin
Year
2017
Author
Lin, D;Luo, Y;Yang, G;Li, F;Xie, X;Chen, D;He, L;Wang, J;Ye, C;Lu, S;Lv, L;Liu, S;He, J;
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Biochem. Pharmacol.
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Potent influenza A virus entry inhibitors targeting a conserved region of hemagglutinin
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2017
Author
Lin, D;Luo, Y;Yang, G;Li, F;Xie, X;Chen, D;He, L;Wang, J;Ye, C;Lu, S;Lv, L;Liu, S;He, J;
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Biochem. Pharmacol.
Title
Redox-responsive biodegradable polycation poly (amido amine) used as intranasal vaccine delivery systems
Year
2017
Author
Guo, Z;Li, S;Lv, M;Liu, Z;Xue, W;
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ACS Biomaterials Science & Engineering
Title
Reversible Self-Assembled Monolayers (rSAMs): Adaptable Surfaces for Enhanced Multivalent Interactions and Ultrasensitive Virus Detection.
Year
2017
Author
Yeung, SY;Mucha, A;Deshmukh, R;Boutrus, M;Arnebrant, T;Sellergren, B;
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ACS Cent Sci
Title
Self-assembled star-shaped chiroplasmonic gold nanoparticles for an ultrasensitive chiro-immunosensor for viruses
Year
2017
Author
Ahmed, SR;Nagy, E;Neethirajan, S;
Journal
RSC Advances
Title
Structure-activity relationships of 3-O-β-chacotriosyl oleanic acid derivatives as entry inhibitors for highly pathogenic H5N1 influenza virus
Year
2017
Author
Li, S;Jia, X;Shen, X;Wei, Z;Jiang, Z;Liao, Y;Guo, Y;Zheng, X;Zhong, G;Song, G;
Journal
Bioorg. Med. Chem.
Title
Structure-activity relationships of 3-O-β-chacotriosyl oleanic acid derivatives as entry inhibitors for highly pathogenic H5N1 influenza virus
Year
2017
Author
Li, S;Jia, X;Shen, X;Wei, Z;Jiang, Z;Liao, Y;Guo, Y;Zheng, X;Zhong, G;Song, G;
Journal
Bioorg. Med. Chem.
Title
Targeting Influenza Virus Hemagglutinin to Xcr1(+) Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
Year
2017
Author
Gudjonsson, A;Lysén, A;Balan, S;Sundvold-Gjerstad, V;Arnold-Schrauf, C;Richter, L;Bækkevold, ES;Dalod, M;Bogen, B;Fossum, E;
Journal
J. Immunol
Title
The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3
Year
2017
Author
Qian, W;Wei, X;Guo, K;Li, Y;Lin, X;Zou, Z;Zhou, H;Jin, M;
Journal
Front Immunol
Title
An oligothiophene compound neutralized influenza A viruses by interfering with hemagglutinin
Year
2017
Author
Shen, X;Zhu, Z;Ding, Y;Wu, W;Yang, J;Liu, S;
Journal
Biochim. Biophys. Acta
Title
An oligothiophene compound neutralized influenza A viruses by interfering with hemagglutinin
Year
2017
Author
Shen, X;Zhu, Z;Ding, Y;Wu, W;Yang, J;Liu, S;
Journal
Biochim. Biophys. Acta
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Year
2017
Author
Yasuhara, A;Yamayoshi, S;Soni, P;Takenaga, T;Kawakami, C;Takashita, E;Sakai-Tagawa, Y;Uraki, R;Ito, M;Iwatsuki-Horimoto, K;Sasaki, T;Ikuta, K;Yamada, S;Kawaoka, Y;
Journal
Sci Rep
Title
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
Year
2017
Author
Gaya, M;Barral, P;Burbage, M;Aggarwal, S;Montaner, B;Warren Navia, A;Aid, M;Tsui, C;Maldonado, P;Nair, U;Ghneim, K;Fallon, PG;Sekaly, RP;Barouch, DH;Shalek, AK;Bruckbauer, A;Strid, J;Batista, FD;
Journal
Cell
Title
Optoelectronic fowl adenovirus detection based on local electric field enhancement on graphene quantum dots and gold nanobundle hybrid
Year
2017
Author
Ahmed, SR;Mogus, J;Chand, R;Nagy, E;Neethirajan, S;
Journal
Biosens Bioelectron
Title
Optoelectronic fowl adenovirus detection based on local electric field enhancement on graphene quantum dots and gold nanobundle hybrid
Year
2017
Author
Ahmed, SR;Mogus, J;Chand, R;Nagy, E;Neethirajan, S;
Journal
Biosens Bioelectron
Title
Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
Year
2017
Author
Sutton, TC;Chakraborty, S;Mallajosyula, VVA;Lamirande, EW;Ganti, K;Bock, KW;Moore, IN;Varadarajan, R;Subbarao, K;
Journal
NPJ Vaccines
Title
A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA
Year
2018
Author
Bangaru, S;Zhang, H;Gilchuk, IM;Voss, TG;Irving, RP;Gilchuk, P;Matta, P;Zhu, X;Lang, S;Nieusma, T;Richt, JA;Albrecht, RA;Vanderven, HA;Bombardi, R;Kent, SJ;Ward, AB;Wilson, IA;Crowe, JE;
Journal
Nat Commun
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin
Year
2018
Author
Hauck, NC;Kirpach, J;Kiefer, C;Farinelle, S;Maucourant, S;Morris, SA;Rosenberg, W;He, FQ;Muller, CP;Lu, IN;
Journal
Viruses
Title
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses
Year
2018
Author
Ahmed, S;Neethirajan, S;
Journal
Global Challenges
Title
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses
Year
2018
Author
Ahmed, S;Neethirajan, S;
Journal
Global Challenges
Title
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses
Year
2018
Author
Ahmed, S;Neethirajan, S;
Journal
Global Challenges
Title
Development of a high-throughput assay to detect antibody inhibition of low pH induced conformational changes of influenza virus hemagglutinin
Year
2018
Author
Trost, JF;LeMasters, EH;Liu, F;Carney, P;Lu, X;Sugawara, K;Hongo, S;Stevens, J;Steinhauer, DA;Tumpey, T;Katz, JM;Levine, MZ;Li, ZN;
Journal
PLoS ONE
Title
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza
Year
2018
Author
Zhao, H;To, KKW;Chu, H;Ding, Q;Zhao, X;Li, C;Shuai, H;Yuan, S;Zhou, J;Kok, KH;Jiang, S;Yuen, KY;
Journal
Nat Commun
Title
Eliciting unnatural immune responses by activating cryptic epitopes in viral antigens
Year
2018
Author
Lee, YJ;Yu, JE;Kim, P;Lee, JY;Cheong, YC;Lee, YJ;Chang, J;Seong, BL;
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FASEB J.
Title
Eliciting unnatural immune responses by activating cryptic epitopes in viral antigens
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2018
Author
Lee, YJ;Yu, JE;Kim, P;Lee, JY;Cheong, YC;Lee, YJ;Chang, J;Seong, BL;
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FASEB J.
Title
Eliciting unnatural immune responses by activating cryptic epitopes in viral antigens
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2018
Author
Lee, YJ;Yu, JE;Kim, P;Lee, JY;Cheong, YC;Lee, YJ;Chang, J;Seong, BL;
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FASEB J.
Title
Highly Sensitive and Automated SERS-based Immunoassay for H5N1 Detection with Digital Microfluidics
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2018
Author
Wang, Y;Ruan, Q;Lei, ZC;Lin, SC;Zhu, Z;Zhou, L;Yang, CJ;
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Anal. Chem.
Title
Host Cell Mimic Polymersomes for Rapid Detection of Highly Pathogenic Influenza Virus via a Viral Fusion and Cell Entry Mechanism
Year
2018
Author
Kim, H;Na, W;Yeom, M;Choi, J;Kim, J;Lim, J;Yun, D;Chun, H;Park, G;Park, C;Kim, J;Jeong, D;Le, V;Lee, K;Lee, J;Jeong, H;Song, D;Haam, S;
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Adv. Funct. Mater.
Title
Host Cell Mimic Polymersomes for Rapid Detection of Highly Pathogenic Influenza Virus via a Viral Fusion and Cell Entry Mechanism
Year
2018
Author
Kim, H;Na, W;Yeom, M;Choi, J;Kim, J;Lim, J;Yun, D;Chun, H;Park, G;Park, C;Kim, J;Jeong, D;Le, V;Lee, K;Lee, J;Jeong, H;Song, D;Haam, S;
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Adv. Funct. Mater.
Title
Inactivation of influenza A virus via exposure to silver nanoparticle-decorated silica hybrid composites
Year
2018
Author
Park, S;Ko, YS;Lee, SJ;Lee, C;Woo, K;Ko, G;
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Environ Sci Pollut Res Int
Title
Magnetic Nanozyme-Linked Immunosorbent Assay for Ultrasensitive Influenza A Virus Detection
Year
2018
Author
Oh, S;Kim, J;Tran, VT;Lee, DK;Ahmed, SR;Hong, JC;Lee, J;Park, EY;Lee, J;
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ACS Appl Mater Interfaces
Title
Native human monoclonal antibodies with potent cross-lineage neutralization of influenza B viruses
Year
2018
Author
Vigil, A;Estélles, A;Kauvar, LM;Johnson, SK;Tripp, RA;Wittekind, M;
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Antimicrob. Agents Chemother.
Title
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses
Year
2018
Author
Pardi, N;Hogan, MJ;Naradikian, MS;Parkhouse, K;Cain, DW;Jones, L;Moody, MA;Verkerke, HP;Myles, A;Willis, E;LaBranche, CC;Montefiori, DC;Lobby, JL;Saunders, KO;Liao, HX;Korber, BT;et al.
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J. Exp. Med.
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Protective effect of a polyvalent influenza DNA vaccine in pigs
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2018
Author
Karlsson, I;Borggren, M;Rosenstierne, MW;Trebbien, R;Williams, JA;Vidal, E;Vergara-Alert, J;Foz, DS;Darji, A;Sisteré-Oró, M;Segalése, J;Nielsen, J;Fomsgaard, A;
Journal
Veterinary Immunology and Immunopathology
Title
Quantification of Multivalency in Protein-Oligomer-Coated Nanoparticles Targeting Dynamic Membrane Glycan Receptors
Year
2018
Author
Lin, J;Wang, K;Xia, X;Shen, L;
Journal
Langmuir
Title
Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice
Year
2018
Author
Luo, Y;Mohan, T;Zhu, W;Wang, C;Deng, L;Wang, BZ;
Journal
Sci Rep
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
Year
2018
Author
Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B;
Journal
J. Immunol.
Title
Structural presentation of influenza epitopes on modular virus-like particles
Year
2018
Author
Doan, T;
Journal
espace.library.uq.edu.au
Title
The Cranberry Extract Oximacro® Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin
Year
2018
Author
Luganini, A;Terlizzi, ME;Catucci, G;Gilardi, G;Maffei, ME;Gribaudo, G;
Journal
Front Microbiol
Title
The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector
Year
2018
Author
Lebedeva, E;Bagaev, A;Pichugin, A;Chulkina, M;Lysenko, A;Tutykhina, I;Shmarov, M;Logunov, D;Naroditsky, B;Ataullakhanov, R;
Journal
BMC Immunol.
Title
The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis
Year
2018
Author
Zheng, Z;Paul, S;Mo, X;Yuan, Y;Tan, Y;
Journal
Preprints
Title
The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis
Year
2018
Author
Zheng, Z;Paul, S;Mo, X;Yuan, Y;Tan, Y;
Journal
Preprints
Title
Preclinical evaluation of the efficacy of an H5N8 vaccine candidate (IDCDC-RG43A) in mouse and ferret models for pandemic preparedness
Year
2018
Author
Jeong, J;Kim, E;Lloren, K;Kwon, J;Kwon, H;Ahn, S;Kim, Y;Choi, W;Si, Y;Lee, O;Han, H;Baek, Y;Song, M;Choi, Y;Kim, C;
Journal
Vaccine
Title
Quantifying Weak Glycan-Protein Interactions Using a Biolayer Interferometry Competition Assay: Applications to ECL Lectin and X-31 Influenza Hemagglutinin
Year
2018
Author
Ji, Y;Woods, RJ;
Journal
Adv. Exp. Med. Biol.
Title
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Year
2019
Author
Lee, J;Paparoditis, P;Horton, AP;Frühwirth, A;McDaniel, JR;Jung, J;Boutz, DR;Hussein, DA;Tanno, Y;Pappas, L;Ippolito, GC;Corti, D;Lanzavecchia, A;Georgiou, G;
Journal
Cell Host Microbe
Title
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Year
2019
Author
Lee, J;Paparoditis, P;Horton, AP;Frühwirth, A;McDaniel, JR;Jung, J;Boutz, DR;Hussein, DA;Tanno, Y;Pappas, L;Ippolito, GC;Corti, D;Lanzavecchia, A;Georgiou, G;
Journal
Cell Host Microbe
Title
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Year
2019
Author
Lee, J;Paparoditis, P;Horton, AP;Frühwirth, A;McDaniel, JR;Jung, J;Boutz, DR;Hussein, DA;Tanno, Y;Pappas, L;Ippolito, GC;Corti, D;Lanzavecchia, A;Georgiou, G;
Journal
Cell Host Microbe
Title
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Year
2019
Author
Lee, J;Paparoditis, P;Horton, AP;Frühwirth, A;McDaniel, JR;Jung, J;Boutz, DR;Hussein, DA;Tanno, Y;Pappas, L;Ippolito, GC;Corti, D;Lanzavecchia, A;Georgiou, G;
Journal
Cell Host Microbe
Title
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Year
2019
Author
Lee, J;Paparoditis, P;Horton, AP;Frühwirth, A;McDaniel, JR;Jung, J;Boutz, DR;Hussein, DA;Tanno, Y;Pappas, L;Ippolito, GC;Corti, D;Lanzavecchia, A;Georgiou, G;
Journal
Cell Host Microbe
Title
Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy
Year
2019
Author
Lim, KS;Mohamed, MS;Wang, H;Hartono, ;Hazawa, M;Kobayashi, A;Voon, DC;Kodera, N;Ando, T;Wong, RW;
Journal
Biochim Biophys Acta Gen Subj
Title
Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge
Year
2019
Author
Sisteré-Oró, M;Vergara-Alert, J;Stratmann, T;López-Serrano, S;Pina-Pedrero, S;Córdoba, L;Pérez-Maillo, M;Pleguezuelos, P;Vidal, E;Veljkovic, V;Segalés, J;Nielsen, J;Fomsgaard, A;Darji, A;
Journal
PLoS ONE
Title
Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge
Year
2019
Author
Sisteré-Oró, M;Vergara-Alert, J;Stratmann, T;López-Serrano, S;Pina-Pedrero, S;Córdoba, L;Pérez-Maillo, M;Pleguezuelos, P;Vidal, E;Veljkovic, V;Segalés, J;Nielsen, J;Fomsgaard, A;Darji, A;
Journal
PLoS ONE
Title
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
Year
2019
Author
Andersen, TK;Huszthy, PC;Gopalakrishnan, RP;Jacobsen, JT;Fauskanger, M;Tveita, AA;Grødeland, G;Bogen, B;
Journal
NPJ Vaccines
Title
Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin
Year
2019
Author
Ramage, W;Gaiotto, T;Ball, C;Risley, P;Carnell, GW;
Journal
Antibodies
Title
Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin
Year
2019
Author
Ramage, W;Gaiotto, T;Ball, C;Risley, P;Carnell, GW;
Journal
Antibodies

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We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.