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휴먼 ICAM-2/CD102  항체

All ICAM-2 Reagents

ICAM-2/CD102
반응성: Human  
신청: ELISA  WB  IP  
10332-RP02-50
10332-RP02-200
10332-RP02-100
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200 µg 
100 µg 
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  • Slide 1
  • Slide 1
반응성: Human  
신청: ELISA  
10332-RP01-400
10332-RP01-200
10332-RP01-100
400 µg 
200 µg 
100 µg 
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    반응성: Human  
    신청: 
    10332-R022-50
    10332-R022-100
    10332-R022-1
    50 µg 
    100 µg 
    1 mg 
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      반응성: Human  
      신청: ELISA  
      10332-MM01-50
      10332-MM01-200
      10332-MM01-100
      50 µg 
      200 µg 
      100 µg 
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        반응성: Human  
        신청: ELISA  WB  
        10332-R041-50
        10332-R041-100
        50 µg 
        100 µg 
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        • Slide 1
        반응성: Human  
        신청: WB  
        10332-R033-50
        10332-R033-100
        50 µg 
        100 µg 
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        • Slide 1
        반응성: Human  
        신청: WB  
        10332-R055-50
        10332-R055-100
        50 µg 
        100 µg 
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        • Slide 1
        반응성: Human  
        신청: 
        10332-R015-50
        10332-R015-100
        10332-R015-1
        50 µg 
        100 µg 
        1 mg 
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          반응성: Human  
          신청: IHC-P  
          10332-MM06-50
          10332-MM06-200
          10332-MM06-100
          50 µg 
          200 µg 
          100 µg 
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          • Slide 1
          • Slide 1
          10332-H08HL-300 
          10332-H03HL-300 

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          ICAM-2/CD102 관련 경로

            ICAM-2/CD102 관련 제품

            ICAM-2/CD102 관련 제품

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            ICAM-2/CD102 요약 및 단백질 정보

            ICAM-2/CD102 배경

            유전자 요약: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
            General information above from NCBI
            세포하 위치: Membrane; Single-pass type I membrane protein.
            염기서열 유사성: Belongs to the immunoglobulin superfamily. ICAM family. {ECO:0000305}.; Contains 2 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.
            General information above from UniProt

            Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains, and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As a second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

            ICAM-2/CD102 대체 이름

            CD102, [homo-sapiens]
            CD102,ICAM-2,ICAM2, [human]
            CD102,Icam2,Icam-2,Ly-60,RP23-418O11.10-001, [mouse]
            CD102,Ly-60,Icam-2, [mus-musculus]

            ICAM-2/CD102 관련 연구

          • Weber KS, et al. (2004) Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN. Inflammation. 28(4): 177-88.
          • Tanaka H, et al. (2004) ICAM-2 gene therapy for peritoneal dissemination of scirrhous gastric carcinoma. Clin Cancer Res. 10(14): 4885-92.
          • Younis AI, et al. (2005) Intercellular adhesion molecule-2 (ICAM-2) in experimental trichinosis. J Egypt Soc Parasitol. 35(3): 1019-26.
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