IL-33 cDNA Clone: Expression and Clone Vector / Plasmid

IL-33 cDNA / Gene Overview

IL33 gene / cDNA is a protein-coding gene which located on 9p24.1. The IL33 gene is conserved in chimpanzee, dog, cow, mouse, and rat.112 organisms have orthologs with human gene IL33.

IL-33 cDNA / Gene Function

The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

IL-33 cDNA / Gene Sequence

LOCUS
LOCUS NM_033439 2718 bp mRNA linear PRI 05-AUG-2018
DEFINITION
Homo sapiens interleukin 33 (IL33), transcript variant 1, mRNA.
ACCESSION
NM_033439
VERSION
NM_033439.3

This sequence information is just for reference only.

IL-33 Family & Reagents

Gene family

IL-33 Gene family reagents (Interleukins)

Approved Symbol Reagent list
IL5
IL1A
IL13
IL12A
IL1RN
IL10
IL9
IL22
IL25
IL1F10
Approved Symbol Reagent list
IL34
IL32
IL36B
IL15
IL16
IL19
IL36A
IL4
CXCL8
IL36G

IL-33 cDNA / Gene Alias

  • DKFZp586H0523
  • DVS27
  • DVS27-related protein
  • IL1F11
  • interleukin-1 family
  • member 11
  • NF-HEV
  • nuclear factor for high endothelial venules

IL-33 cDNA / Gene Expression

Ubiquitous expression in urinary bladder (RPKM 34.7), lung (RPKM 27.3) and 23 other tissues

Recombinant IL-33 protein citations

Title
Upregulation of interleukin-33 in the epidermis of two Japanese patients with Netherton syndrome
Year
2014
Author
Konishi, T;Tsuda, T;Sakaguchi, Y;Imai, Y;Ito, T;Hirota, S;Yamanishi, K;
Journal
J. Dermatol.