Anti-ST2/IL-1 RL1 Antibody


Anti-ST2/IL-1 RL1 Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-ST2/IL-1 RL1 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse ST2/IL-1 RL1
Recombinant Mouse IL1RL1/IL‑1 R4/ST2 Protein (Catalog#51143-M08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL1RL1/IL‑1 R4/ST2 (rM IL1RL1/IL‑1 R4/ST2; Catalog#51143-M08H; NP_001020773.1; Met1-Arg332).
Monoclonal Rabbit IgG Clone #006
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-ST2/IL-1 RL1 Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-ST2/IL-1 RL1 Antibody: Alternative Names

Anti-DER4 Antibody; Anti-Fit-1 Antibody; Anti-Ly84 Antibody; Anti-St2 Antibody; Anti-St2-rs1 Antibody; Anti-ST2L Antibody; Anti-T1 Antibody; Anti-T1/ST2 Antibody

ST2/IL-1 RL1 Background Information

IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.
Full Name
interleukin 1 receptor-like 1
  • Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
  • Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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