Anti-Interferon alpha 2 / IFNA2 Antibody

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Anti-Interferon alpha 2 / IFNA2 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Interferon alpha 2 / IFNA2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Interferon alpha 2 / IFNA2
Immunogen
Recombinant Human Interferon alpha 2 / IFNA2 Protein (Catalog#13833-HNAY)
Preparation
Produced in rabbits immunized with purified, recombinant Human Interferon alpha 2 / IFNA2 (rh Interferon alpha 2 / IFNA2; Catalog#13833-HNAY; NP_000596.2; Cys24-Glu188). Interferon alpha 2 / IFNA2 specific IgG was purified by Human Interferon alpha 2 / IFNA2 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Interferon alpha 2 / IFNA2 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Interferon alpha 2 / IFNA2 Antibody: Alternative Names

Anti-IFN-alphaA Antibody; Anti-IFNA Antibody; Anti-IFNA2B Antibody; Anti-IFNAB Antibody; Anti-INFA2 Antibody; Anti-Interferon alpha 2 Antibody

Interferon alpha 2 / IFNA2 Background Information

Type I Interferons (IFNs) are well known cytokines which exert antiviral activity, antitumor activity and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among IFN-α genes, a total of 28 different sequence variants have been described.The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.
Full Name
interferon, alpha 2
References
  • Wang, et al. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.
  • Groopman JE, et al. (1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med. 100(5): 671-6.
  • Krueger JM, et al. (1987) Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 9(1): 23-30.
  • Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions
    Author
    Du, J;Rehm, BHA;
    Year
    2017
    Journal
    Microb. Cell Fact.

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