CD218a antigens

CD218a antigens general information

CD218a Gene ID 8809
CD218a Official Full Name interleukin 18 receptor 1
CD218a Alias IL-18Rα, IL-1Rrp, IL18R1
CD218a Cellular Expression T; B; NK; Dendritic; Endothelial; Granulocyte; Macrophage; monocytes
CD218a Ligand/Receptor/Association IL-18
CD218a Function Forms part of the receptor complex for IL18
CD218a Summary The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Information from NCBI or Wiki

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