CD235a antigens

CD235a antigens general information

CD235a Gene ID 2993
CD235a Official Full Name glycophorin A (MNS blood group)
CD235a Alias Glycophorin A, GYPA
CD235a Cellular Expression Erythrocyte; Stem cell
CD235a Ligand/Receptor/Association hepatitis A virus, babesia, P. falciparum
CD235a Function Major erythrocyte intrinsic membrane protein. Minimizes erythrocyte aggregation, receptor for influenza virus, Plasmodium falciparum and Hepatitis A virus
CD235a Summary Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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