| CD242 Gene ID | 3386 |
| CD242 Official Full Name | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| CD242 Alias | ICAM-4 |
| CD242 Cellular Expression | Endothelial; Erythrocyte; Stem cell |
| CD242 Ligand/Receptor/Association | CD11a, b; CD18; CD49b, d, e, CD51 |
| CD242 Function | Ligand for the leukocyte adhesion protein LFA-1 |
| CD242 Summary | This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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