CD247 antigens

CD247 antigens general information

CD247 Gene ID 919
CD247 Official Full Name CD247 molecule
CD247 Alias TCRz, CD3-ZEETA
CD247 Cellular Expression T; NK; Stem cell
CD247 Ligand/Receptor/Association  
CD247 Function Couples antigen recognition to several intracellular signaling pathways
CD247 Summary The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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