CD277 antigens

CD277 antigens general information

CD277 Gene ID 11119
CD277 Official Full Name butyrophilin subfamily 3 member A1
CD277 Alias BTN3A1, butyrophilin SF3 A1, BTF5
CD277 Cellular Expression T; B; NK; Dendritic; Endothelial; Macrophage; monocytes; Stem cell
CD277 Ligand/Receptor/Association BT3.1-R
CD277 Function T-cell activation
CD277 Summary The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

Information from NCBI or Wiki

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