| CD298 Gene ID | 483 |
| CD298 Official Full Name | ATPase Na+/K+ transporting subunit beta 3 |
| CD298 Alias | ATP1B3, ATPB-3 |
| CD298 Cellular Expression | |
| CD298 Ligand/Receptor/Association | dimerizes with ATPα1, 2 or 3 |
| CD298 Function | Component of Na+-K+ pump on neuronal membranes. |
| CD298 Summary | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008] |
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