CD314 antigens

CD314 antigens general information

CD314 Gene ID 22914
CD314 Official Full Name killer cell lectin like receptor K1
CD314 Alias NKG2D, KLRK1
CD314 Cellular Expression T; B; NK; Granulocyte; Macrophage
CD314 Ligand/Receptor/Association MICA, MICB, ULBP-1,2,3
CD314 Function Receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells
CD314 Summary The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Information from NCBI or Wiki

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