CD316 antigens

CD316 antigens general information

CD316 Gene ID 93185
CD316 Official Full Name immunoglobulin superfamily member 8
CD316 Alias EWI2, PGRL, CD81P3, KASP,IGSF8, EWI-2, KCT-4
CD316 Cellular Expression T; B; NK
CD316 Ligand/Receptor/Association  
CD316 Function Negative regulator of cell motility.
CD316 Summary This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

Information from NCBI or Wiki

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