CD32 Gene ID | |
CD32 Official Full Name | |
CD32 Alias | FCG2, FCGR2A1, FCGR2 |
CD32 Cellular Expression | T; B; Endothelial; Dendritic cell; Granulocyte; Macrophage; monocytes |
CD32 Ligand/Receptor/Association | aggregated IgG, phosphatases |
CD32 Function | Regulation of B-cell function. Induces phagocytosis and mediator release. |
CD32 Summary | CD32 is a surface receptor protein and part of a large population of B cell co-receptors, which act to modulate signaling. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loop acts to lower the production of IgG by B cells when there is a surplus in the body. |
Information from NCBI or Wiki