| CD322 Gene ID | 67374 |
| CD322 Official Full Name | junction adhesion molecule 2 |
| CD322 Alias | JAM-B, JAM-2, VE-JAM |
| CD322 Cellular Expression | Endothelial |
| CD322 Ligand/Receptor/Association | PAR-3, a4b1 integrin, JAM3, JAM-2 |
| CD322 Function | May play a role in lymphocyte homing to secondary lymphoid organs |
| CD322 Summary | CD322 / cluster of differentiation 322 as known as Junctional adhesion molecule B, is a protein that in humans is encoded by the JAM2 gene. CD322 represent one mode of cell-to-cell adhesion in endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. |
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