CD344 antigens

CD344 antigens general information

CD344 Gene ID 8322
CD344 Official Full Name frizzled class receptor 4
CD344 Alias Frizzled-4, Fz-4, FzD4
CD344 Cellular Expression Endothelial; Epithelial; Stem cell
CD344 Ligand/Receptor/Association Norrin, Wnt proteins
CD344 Function Receptor for Wnt proteins
CD344 Summary This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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