CD355 antigens

CD355 antigens general information

CD355 Gene ID 56253
CD355 Official Full Name cytotoxic and regulatory T-cell molecule
CD355 Alias CRTAM
CD355 Cellular Expression T; B; NK
CD355 Ligand/Receptor/Association Necl2
CD355 Function Interaction with CADM1 promotes NK cell cytotoxicity and IFN-gamma secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo
CD355 Summary The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]

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