| CD355 Gene ID | 56253 |
| CD355 Official Full Name | cytotoxic and regulatory T-cell molecule |
| CD355 Alias | CRTAM |
| CD355 Cellular Expression | T; B; NK |
| CD355 Ligand/Receptor/Association | Necl2 |
| CD355 Function | Interaction with CADM1 promotes NK cell cytotoxicity and IFN-gamma secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo |
| CD355 Summary | The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009] |
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