CD3d antigens

CD3d antigens general information

CD3d Gene ID 915
CD3d Official Full Name CD3d molecule
CD3d Alias T3D, IMD19, CD3-DELTA
CD3d Cellular Expression T
CD3d Ligand/Receptor/Association assoc. w/CD3/TCR complex
CD3d Function T-cell activation signaling and regulation of TCR expression
CD3d Summary The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.