CD41 antigens

CD41 antigens general information

CD41 Gene ID 3674
CD41 Official Full Name integrin subunit alpha 2b
CD41 Alias ITGA2B, GP2B, HPA3, CD41B, GPIIb, BDPLT2, BDPLT16, PPP1R93
CD41 Cellular Expression T; B
CD41 Ligand/Receptor/Association fibrinogen, fibronectin, vWF and thrombospondin
CD41 Function cell adhesion, cell-cell signalling
CD41 Summary This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.