CD47 antigens

CD47 antigens general information

CD47 Gene ID 16423
CD47 Official Full Name CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
CD47 Alias IAP, MER6
CD47 Cellular Expression T; B; NK; Endothelial; Epithelial; Erythrocyte; Granulocyte; Macrophage; Platelet
CD47 Ligand/Receptor/Association CD172a, CD172g
CD47 Function Cell adhesion and signal transduction
CD47 Summary CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily[1] and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).[2] CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. CD47 is ubiquitously expressed in human cells and has been found to be overexpressed in many different tumor cells.[2][3]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.