CD62P antigens

CD62P antigens general information

CD62P Gene ID 6403
CD62P Official Full Name selectin P
CD62P Alias P-selectin, PADGEM, SELP, LECAM3
CD62P Cellular Expression Endothelial; Platelet
CD62P Ligand/Receptor/Association CD162, CD24, CD57, CD15u
CD62P Function Cell adhesion
CD62P Summary This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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