CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
| Name | Name in pathway | Alias | Function |
|---|---|---|---|
| CD95 | Fas | Apo-1, FASLG, APTL, TNFRSF6 | Induces apoptosis |
| CD120a | TNFR1 | TNFR-I, TNFRSF1A, TNFR1 | Receptor for TNF |
| CD178 | FASL | FasL, CD95L, FASLG, Fas Ligand | T-cell mediated cytotoxicity |
| CD253 | TRAIL | TRAIL, Apo-2L, TL2, TNFSF10 | Induces cell death by apoptosis |
| CD261 | DR4 | TRAIL-R1, DR4, TNFRSF10A | Induces apoptosis, promotes activation of NFkB |
| CD262 | DR5 | TRAIL-R2, DR5, TNFRSF10B | Activated by TNFSF10 / TRAIL and transduces apoptosis signal |
| CD264 | DcR2 | DCR2, TRAIL-R4, TNFRSF10D | Receptor for TRAIL, inhibits apoptosis |
| CD271 | P75 | NGFR, p75 (NTR) | Regulates neuronal growth, migration, differentiation and cell death during stem cells. |
| CD358 | DR6 | TNFRSF21 | May activate NFkB and promote apoptosis. May activate JNK and be lymphocytes. involved in T-cell differentiation. Required for both normal cell body death and axonal pruning |
