CD antigens related to Jak-Stat Signaling Pathway

CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.

Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.

CD antigens chart related to Jak-Stat Signaling Pathway

Name Name in pathway Alias Function
CD25 Growth Factor Tac, p55, IL2RA Receptor for IL2
CD45 PTPase LCA, T200, B220, PTPRC Critical for B- and T-cell receptor mediated activation. Regullar of cell growth and differentiation
CD114 Cytokine GCSFR, CSF3R Myeloid cell proliferation and differentiation
CD115 Cytokine M-CSFR, c-fms, CSF1R Monocytic cell proliferation and differentiation
CD122 Growth Factor IL-2Rβ, IL-2RB Receptor for IL2 and IL15
CD123 Growth Factor IL-3R, IL3RA Receptor for IL3
CD124 Growth Factor IL4RA, IL4R Receptor for IL4 and IL13
CD125 Growth Factor IL5RA, IL5R Receptor for IL5
CD126 Growth Factor IL-6R, IL6R, gp80 Receptor for IL6
CD127 Growth Factor IL-7R, IL7R Receptor for IL7
CD130 Growth Factor IL-6Rβ, gp130, IL6ST Transmits activities of IL6, IL11, LIF and CNF
CD191 Cytokine CCR1, MIP-1αR, RANTES-R Chemotaxis, adhesion
CD192 Cytokine CCR2, MCP-1-R Leukocyte chemotaxis and is an HIV co-receptor
CD212 Growth Factor IL-12-R β1, IL12RB1 Forms part of the receptor complexes for IL12 and IL23
CD213a1 Growth Factor IL-13-R α1, IL13RA1 Forms part of the receptor complexes for IL13 and IL4
CD215 Growth Factor IL15RA Receptor for IL15.
CD221 Growth Factor IGF-1 R, IGF1R Receptor for IGF-I and IGF-II. Mediates mitogenic and anti-apoptotic signals
CD360 Growth Factor IL-21R Receptor for interleukin-21.