CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
| Name | Name in pathway | Alias | Function |
|---|---|---|---|
| CD3e | T3E | T3E, TCRE, CD3 epsilon | T-cell activation signaling and regulation of TCR expression |
| CD11a | Integrins | LFA-1, LFA1A, ITGAL | Intracellular adhesion and costimulation. |
| CD11c | Integrins | p150,95, CR4, integrin αX, LFA-1A, ITGAX | Cell adhesion |
| CD18 | Integrins | Integrin β2, ITGB2, MFI7 | Adhesion, cell signaling |
| CD29 | Integrins | Integrin β1, ITGB1, FNRB | Lymphocyte and endothelial adhesion, lymphocyte trafficking and transvascular migration |
| CD41 | Integrins | ITGA2B | Platelet activation and aggregation. |
| CD49b | Integrins | VLA-2, ITGA2 | Adhesion and platelet aggregation. |
| CD49c | Integrins | VLA-3, ITGA3 | Adhesion and signal transduction |
| CD49e | Integrins | VLA-5, ITGA5 | Adhesion, regulation of cell survival and apoptosis |
| CD49f | Integrins | VLA-6, ITGA6 | Embryogenesis, adhesion and cell migration |
| CD51 | Integrins | Vitronectin receptor, ITGAV, MSK8 | Adhesion and signal transduction |
| CD61 | Integrins | GPIIIa, ITGB3, GP3A | Cell adhesion |
| CD82 | KAI1 | R2, KAI1, Tetraspanin-27 | Signal transduction |
| CD98 | SLC3A2 | 4F2hc, SLC3A2, MDU1 | Cell activation and cell aggregation |
| CD103 | Integrins | HUMINAE, ITGA1 | Lymphocyte retention. Receptor for E-cadherin. |
| CD120a | TNFRSF1A | TNFR-I, TNFRSF1A, TNFR1 | Receptor for TNF |
| CD120b | TNFRSF1B | TNFR-II, TNFRSF1B, TNFR2 | Receptor for TNF. Involved in cell differentiation, apoptosis and necrosis |
| CD154 | CD40L | CD40L, CD40 Ligand, gp39, TRAP | Mediates B-cell proliferation, IgE production and is involved in immunoglobulin class switching |
| CD242 | Integrins | ICAM-4 | Ligand for the leukocyte adhesion protein LFA-1 |
| CD261 | TNFRSF10A | TRAIL-R1, DR4, TNFRSF10A | Induces apoptosis, promotes activation of NFkB |
