CD antigens related to TNF Signaling

CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.

Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.

CD antigens chart related to TNF Signaling

Name Alias Function
CD27 T14, TNFRSF 7, CD27L receptor Costimulation of B- and T-cell activation
CD30 Ki-1, TNFRSF8 Regulates lymphocyte proliferation and cell death. Activation of NF-κB
CD95 Apo-1, FASLG, APTL, TNFRSF6 Induces apoptosis
CD120a TNFR-I, TNFRSF1A, TNFR1 Receptor for TNF
CD120b TNFR-II, TNFRSF1B, TNFR2 Receptor for TNF. Involved in cell differentiation, apoptosis and necrosis
CD156b ADAM17, ADAM18, CSVP, NISBD, NISBD1, TACE Cleaves transmembrane form of TNF-α to generate the soluble active form.
CD156c ADAM10 Metalloprotease activity, cleaves many proteins including TNF-伪 and E-cadherin
CD156c ADAM10 Metalloprotease activity, cleaves many proteins including TNF-伪 and E-cadherin
CD178 FasL, CD95L, FASLG, Fas Ligand T-cell mediated cytotoxicity
CD253 TRAIL, Apo-2L, TL2, TNFSF10 Induces cell death by apoptosis
CD254 TNFSF11, RANKL, OPGL, ODF Involved in dendritic cell maturation
CD256 APRIL, TALL-2, TRDL-1, TNFSF13 Important for B cell development
CD258 LIGHT, HVEM-L, TNFRSF14 Stimulates T-cell proliferation, receptor for Herpes simplex virus
CD262 TRAIL-R2, DR5, TNFRSF10B Activated by TNFSF10 / TRAIL and transduces apoptosis signal
CD264 DCR2, TRAIL-R4, TNFRSF10D Receptor for TRAIL, inhibits apoptosis
CD265 RANK, TRANCE-R, ODFR, TNFRSF11A Receptor for TRANCE. Enhances T-cell growth and dendritic cell function, plays a role in lymph node organogenesis
CD266 TWEAK-R, FGF-inducible 14, TNFRSF12A Receptor for TWEAK. Promotes angiogenesis and the proliferation of endothelial cells.
CD267 TACI, TNFR SF13B, TNFRSF13B Receptor for CD256 and CD257, mediates activation of the transcription factors NFAT, AP1, and NFkB.
CD269 BCMA, TNFRSF13B, TNFRSF17 Receptor for CD256 and CD257, activates NFkB and JNK.
CD271 NGFR, p75 (NTR) Regulates neuronal growth, migration, differentiation and cell death during stem cells.
CD272 BTLA Lymphocyte inhibitory receptor
CD357 TNFRSF18, GITR Receptor for TNFSF18
CD358 TNFRSF21 May activate NFkB and promote apoptosis. May activate JNK and be lymphocytes. involved in T-cell differentiation. Required for both normal cell body death and axonal pruning