CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
| Name | Alias | Function |
|---|---|---|
| CD27 | T14, TNFRSF 7, CD27L receptor | Costimulation of B- and T-cell activation |
| CD30 | Ki-1, TNFRSF8 | Regulates lymphocyte proliferation and cell death. Activation of NF-κB |
| CD95 | Apo-1, FASLG, APTL, TNFRSF6 | Induces apoptosis |
| CD120a | TNFR-I, TNFRSF1A, TNFR1 | Receptor for TNF |
| CD120b | TNFR-II, TNFRSF1B, TNFR2 | Receptor for TNF. Involved in cell differentiation, apoptosis and necrosis |
| CD156b | ADAM17, ADAM18, CSVP, NISBD, NISBD1, TACE | Cleaves transmembrane form of TNF-α to generate the soluble active form. |
| CD156c | ADAM10 | Metalloprotease activity, cleaves many proteins including TNF-伪 and E-cadherin |
| CD156c | ADAM10 | Metalloprotease activity, cleaves many proteins including TNF-伪 and E-cadherin |
| CD178 | FasL, CD95L, FASLG, Fas Ligand | T-cell mediated cytotoxicity |
| CD253 | TRAIL, Apo-2L, TL2, TNFSF10 | Induces cell death by apoptosis |
| CD254 | TNFSF11, RANKL, OPGL, ODF | Involved in dendritic cell maturation |
| CD256 | APRIL, TALL-2, TRDL-1, TNFSF13 | Important for B cell development |
| CD258 | LIGHT, HVEM-L, TNFRSF14 | Stimulates T-cell proliferation, receptor for Herpes simplex virus |
| CD262 | TRAIL-R2, DR5, TNFRSF10B | Activated by TNFSF10 / TRAIL and transduces apoptosis signal |
| CD264 | DCR2, TRAIL-R4, TNFRSF10D | Receptor for TRAIL, inhibits apoptosis |
| CD265 | RANK, TRANCE-R, ODFR, TNFRSF11A | Receptor for TRANCE. Enhances T-cell growth and dendritic cell function, plays a role in lymph node organogenesis |
| CD266 | TWEAK-R, FGF-inducible 14, TNFRSF12A | Receptor for TWEAK. Promotes angiogenesis and the proliferation of endothelial cells. |
| CD267 | TACI, TNFR SF13B, TNFRSF13B | Receptor for CD256 and CD257, mediates activation of the transcription factors NFAT, AP1, and NFkB. |
| CD269 | BCMA, TNFRSF13B, TNFRSF17 | Receptor for CD256 and CD257, activates NFkB and JNK. |
| CD271 | NGFR, p75 (NTR) | Regulates neuronal growth, migration, differentiation and cell death during stem cells. |
| CD272 | BTLA | Lymphocyte inhibitory receptor |
| CD357 | TNFRSF18, GITR | Receptor for TNFSF18 |
| CD358 | TNFRSF21 | May activate NFkB and promote apoptosis. May activate JNK and be lymphocytes. involved in T-cell differentiation. Required for both normal cell body death and axonal pruning |
