Recombinant Antigens for 2015-2021 Influenza Vaccine Strains

Seasonal flu (influenza) is a common infectious disease of the respiratory tract causing mild to severe illness. Vaccination is the most effective way to prevent seasonal flu. Each year, 3-4 different flu strains will be selected as vaccine strains based on surveillance data of the recent isolates, and the performance of the vaccines from the previous season.

The annual vaccine strains normally include both influenza A and influenza B. There are many subtypes of influenza A based on the subtype of two surface antigens, hemagglutinin (HA) and neuraminidase (NA), while influenza B is divided into two lineages, the Yamagata lineage and the Victoria lineage.

To support influenza research, Sino Biological has developed a panel of recombinant antigen products covering most of the vaccine strains from 2015-2021. The products include both HA and NA proteins, and some nucleoprotein (NP) proteins. Customized production is available if your antigen (or strain) of interest is not on the current list.

Year 2020-2021

  • A/Guangdong-Maonan/SWL1536/2019 (H1N1)
    Egg-based (quadrivalent, trivalent)
    HA: 40717-V08H
    NP: 40723-V08B
  • A/Hong Kong/2671/2019 (H3N2)
    Egg-based (quadrivalent, trivalent)
    HA: 40721-V08H
    NP: 40753-V08B
  • A/Hawaii/70/2019 (H1N1)
    Cell- or recombinant-based (quadrivalent, trivalent)
    HA: 40717-V08H
    NP: 40724-V08B
  • A/Hong Kong/45/2019 (H3N2)
    Cell- or recombinant-based (quadrivalent, trivalent)
    HA: 40765-V08H(Under Development)
    NP: 40754-V08B
  • B/Phuket/3073/2013
    Egg-based,Cell- or recombinant-based (quadrivalent)
    HA: 40498-V08B
    NA: 40502-V07B
    NP: 40500-V08B
  • B/Washington/02/2019
    Egg-based,Cell- or recombinant-base (quadrivalent, trivalent)
    HA: 40722-V08H
    NP: 40755-V08B

Year 2019-2020

Year 2018-2019

Year 2017-2018

Year 2016-2017

Year 2015-2016

Influenza Virus Antigen Information