Inhibin beta A/Activin A Gene Sequence, Family, Fuction and Expression Information

Inhibin beta A/Activin A cDNA / Gene Overview

INHBA gene / cDNA is a protein-coding gene which located on 7p14.1. The INHBA gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, and frog.221 organisms have orthologs with human gene INHBA.

Inhibin beta A/Activin A cDNA / Gene Function

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016]

Inhibin beta A/Activin A cDNA / Gene Sequence

LOCUS
LOCUS NM_002192 6105 bp mRNA linear PRI 05-AUG-2018
DEFINITION
Homo sapiens inhibin subunit beta A (INHBA), mRNA.
ACCESSION
NM_002192
VERSION
NM_002192.3

This sequence information is just for reference only.

Inhibin beta A/Activin A Family & Reagents

Gene family

Inhibin beta A/Activin A Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
CSF3
IL1RN
CALCA
ADIPOQ
VTN
PROK1
vWF
LGALS1
CXCL16
INS
Approved Symbol Reagent list
CCL24
CCL15
CCL1
IGF1
LGALS3
CCL13
CXCL8
NTS
ICOSLG
CXCL12

Inhibin beta A/Activin A cDNA / Gene Expression

Broad expression in endometrium (RPKM 12.3), gall bladder (RPKM 11.3) and 15 other tissues