ADRA2B Protein Overview: Sequence, Structure, Function and Protein Interaction

ADRA2B Protein Overview

Regan et al. (1988) and Lomasney et al. (1990) cloned the ADRA2B gene. By Northern blot analysis of various rat tissues, Lomasney et al. (1990) detected expression of ADRA2B in liver and kidney. Unique pharmacology and tissue localization suggested that this was a previously unidentified subtype.

ADRA2B protein family

Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.

ADRA2B protein name

Recommended name
Alpha-2B adrenergic receptor
Aliases
ADRARL1

ADRA2B Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 1-450 Alpha-2B adrenergic receptor.

Molecular weight (Da)

49953.72

Theoretical pI

8.80

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